2-溴-1,3-二甲苯合成路线 （共 189 条）
反应条件
hydrogen; oxygen T=40°C; P=760 Torr; Irradiationeffect of further reagent; Product distributionMechanism;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 4 p. 775 - 780
反应条件
1: NBS, benzoyl peroxide / CCl4 / 3 h / Heating 2: 1.) hexamine; 2.) conc. HCl / 1.) CHCl3, reflux, 1 h; 2.) 50percent aq. AcOH, reflux, 1 h View Scheme
参考文献
Miyano, Sotaro; Fukushima, Hiroshi; Inagawa, Hideho; Hashimoto, Harukichi
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, p. 3285 - 3286
反应条件
1: in ethylene glycol dimethyl ether 2 h; 2: With iodine in tetrahydrofuran T=20°C; 3 h;
参考文献
Sasaki, Yusuke; Hirabuki, Mariko; Ambo, Akihiro; Ouchi, Hidekazu; Yamamoto, Yutaka
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 3 p. 327 - 329
反应条件
TfOH2+B(OTf)4- in toluene 18 h; Ambient temperature; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 49, # 24 p. 4591 - 4594
反应条件
hydrogen; oxygen T=40°C; P=760 Torr; Irradiationeffect of further reagents; Product distributionMechanism;
参考文献
Cacace, Fulvio; Ciranni, Giovanna; Marzio, Annito Di
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , # 4 p. 775 - 780
反应条件
tris(dibenzylideneacetone)dipalladium (0); ZnF2; tri-tert-butyl phosphine in N,N-dimethyl-formamide T=90°C; 24 h;
参考文献
Wu, Lingyun; Hartwig, John F.
Journal of the American Chemical Society, 2005 , vol. 127, # 45 p. 15824 - 15832
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; bis(η3-allyl-μ-chloropalladium(II)) in 1,3,5-trimethyl-benzene T=20 - 140°C; 10.1667 h; Inert atmosphereSealed tube; chemoselective reaction;
参考文献
Shang, Rui; Ji, Dong-Sheng; Chu, Ling; Fu, Yao; Liu, Lei
Angewandte Chemie - International Edition, 2011 , vol. 50, # 19 p. 4470 - 4474
反应条件
1: (i) Mg, (ii) /BRN= 1900390/ 3: LiAlH4 4: SOCl2 5: aq. ethanol View Scheme
参考文献
Loefgren,N. et al.
Acta Chemica Scandinavica (1947-1973), 1963 , vol. 17, p. 1252 - 1261
反应条件
potassium phosphate; (1,2,3,4,5-pentaphenylferrocen-1'-yl)-di-tert-butylphosphine; palladium diacetate in tetrahydrofuran T=100°C; 4 h; Inert atmosphere;
参考文献
Nakao, Yoshiaki; Takeda, Masahide; Matsumoto, Takuya; Hiyama, Tamejiro
Angewandte Chemie - International Edition, 2010 , vol. 49, # 26 p. 4447 - 4450
反应条件
tris-(dibenzylideneacetone)dipalladium(0); (1,2,3,4,5-pentaphenylferrocen-1'-yl)-di-tert-butylphosphine in toluene T=20°C; 1 h;
参考文献
Vila, Carlos; Giannerini, Massimo; Hornillos, Valentin; Fananas-Mastral, Martin; Feringa, Ben L.
Chemical Science, 2014 , vol. 5, # 4 p. 1361 - 1367
