4'-羟基联苯-4-羧酸合成路线 （共 65 条）
反应条件
1: With potassium hydroxide in ethanol; water 24 h; Inert atmosphereReflux; 2: With hydrogenchloride in ethanol; water pH=6;
参考文献
Yao, Jianzhong; Liu, Hongming; Zhou, Ting; Chen, Hai; Miao, Zhenyuan; Dong, Guoqiang; Wang, Shengzheng; Sheng, Chunquan; Zhang, Wannian
Tetrahedron, 2012 , vol. 68, # 14 p. 3074 - 3085
反应条件
hydrogenchloride; sodium hydroxide in water; dimethyl sulfoxide
参考文献
Merck and Co., Inc.
Patent: US5741775 A1, 1998 ;
反应条件
1.1: 97 percent / sulfuric acid / 6 h / Heating 2.1: potassium carbonate / butan-2-one / 6 h / Heating 2.2: aq. potassium hydroxide / ethanol; H2O / 0.5 h / Heating 2.3: 74 percent / aq. HCl / H2O / 3 h / Heating View Scheme
参考文献
Gray et al.
Journal of the Chemical Society, 1955 , p. 1412,1414, 1418, 1420
参考文献
Fieser; Bradsher
Journal of the American Chemical Society, 1936 , vol. 58, p. 1738,1740
参考文献
Gray et al.
Journal of the Chemical Society, 1955 , p. 1412,1414, 1418, 1420
反应条件
sulfuric acid
T=80°C; 4 h;
参考文献
MITSUBISHI GAS CHEMICAL COMPANY, INC.
Patent: EP1380567 A1, 2004 ;
Location in patent: Page 5 ;
反应条件
sulfuric acid; acetic anhydride in water
参考文献
Mitsubishi Gas Chemical Co., Inc.
Patent: US2003/124268 A1, 2003 ;
反应条件
sulfuric acid
T=80°C; 4 h;
参考文献
Mitsubishi Gas Chemical Co., Inc.
Patent: US6677475 B2, 2004 ;
Location in patent: Page column 10 ;
反应条件
1: 4'-hydroxy-biphenyl-4-carboxylic acid With potassium hydroxide in ethanol; water
1 h; Reflux;
2: 1-n-heptylbromide With potassium iodide in ethanol; water
36 h; Reflux;
3: With sulfuric acid in water
参考文献
Marini; Domenici; Malanga; Menicagli; Veracini
Tetrahedron, 2010 , vol. 66, # 19 p. 3472 - 3477
参考文献
Gray et al.
Journal of the Chemical Society, 1955 , p. 1412,1414, 1418, 1420
