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结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
对溴溴苄
合成路线
(共 313 条)
589-15-1
对溴溴苄
→
反应条件
23958-29-4
+
18869-30-2
4,4'-二溴-反-芪
反应条件
sodium hydrogencarbonate; dimethyl sulfoxide; triphenylphosphine; potassium iodide T=140°C; 40 h; Inert atmosphere; optical yield given as percent de;
参考文献
Saiyed, Akeel S.; Patel, Krupa N.; Kamath, Bola V.; Bedekar, Ashutosh V.
Tetrahedron Letters, 2012 , vol. 53, # 35 p. 4692 - 4696
51044-13-4
(4-溴苄基)三苯基溴化磷鎓
+
589-15-1
对溴溴苄
→
反应条件
23958-29-4
+
18869-30-2
4,4'-二溴-反-芪
反应条件
sodium hydrogencarbonate; dimethyl sulfoxide; potassium iodide T=140°C; 40 h; Inert atmosphere; optical yield given as percent de;
参考文献
Saiyed, Akeel S.; Patel, Krupa N.; Kamath, Bola V.; Bedekar, Ashutosh V.
Tetrahedron Letters, 2012 , vol. 53, # 35 p. 4692 - 4696
98-88-4
苯甲酰氯
+
589-15-1
对溴溴苄
→
反应条件
22421-88-1
2-(4-溴苯基)-1-苯基乙酮
反应条件
1: 4-bromo-benzyl bromide With manganese in tetrahydrofuran T=20°C; Metallation; 0.333333 h; 2: benzoyl chloride in tetrahydrofuran T=20°C; Substitution; 2 h;
参考文献
Kim, Seung-Hoi; Rieke, Reuben D.
Journal of Organic Chemistry, 2000 , vol. 65, # 8 p. 2322 - 2330
960-16-7
三丁基苯基锡
+
589-15-1
对溴溴苄
+
13939-06-5
→
反应条件
22421-88-1
2-(4-溴苯基)-1-苯基乙酮
反应条件
palladium(II) dichloride bis[bis(diphenylphosphine)ferrocene] dichloromethane; 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide T=100°C; Stille coupling; 16 h;
参考文献
Saevmarker, Jonas; Lindh, Jonas; Nilsson, Peter
Tetrahedron Letters, 2010 , vol. 51, # 52 p. 6886 - 6889
589-15-1
对溴溴苄
→
反应条件
1762-84-1
反应条件
1: benzene / |Reflux 2: 18-crown-6 ether; potassium carbonate / dichloromethane; water / 24 h / 20 °C 3: 24 h / 250 °C View Scheme
参考文献
Ho, Jinn-Hsuan; Lin, Yu-Chen; Chou, Li-Ting; Chen, Ying-Zhe; Liu, Wei-Qi; Chuang, Chao-Li
Tetrahedron Letters, 2013 , vol. 54, # 15 p. 1991 - 1993
83857-96-9
+
589-15-1
对溴溴苄
→
反应条件
151012-31-6
反应条件
sodium borohydride; potassium carbonate in isobutyramide; water
参考文献
E. I. Du Pont de Nemours and Company; Merck and Co., Inc.
Patent: US5310928 A1, 1994 ;
US 5310928 A
79047-41-9
+
589-15-1
对溴溴苄
→
反应条件
反应条件
potassium carbonate in N,N-dimethyl acetamide
参考文献
Larsen; King; Chen; Corley; Foster; Roberts; Yang; Lieberman; Reamer; Tschaen; Verhoeven; Reider; Lo; Rossano; Brookes; Meloni; Moore; Arnett
Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6391 - 6394
83857-96-9
+
589-15-1
对溴溴苄
→
反应条件
反应条件
sodium tetrahydroborate; potassium carbonate 1.) dimethylacetamide, -10 deg C, 2 h; room temp., 2 h, 2.) MeOH, room temp., 1 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Larsen; King; Chen; Corley; Foster; Roberts; Yang; Lieberman; Reamer; Tschaen; Verhoeven; Reider; Lo; Rossano; Brookes; Meloni; Moore; Arnett
Journal of Organic Chemistry, 1994 , vol. 59, # 21 p. 6391 - 6394
589-15-1
对溴溴苄
+
98-80-6
→
反应条件
2116-36-1
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium carbonate in water; N,N-dimethyl-formamide Suzuki-Miyaura Coupling; 0.216667 h; Microwave irradiationInert atmosphere;
参考文献
Zhang, Yu-Quan
Journal of Chemical Research, 2013 , vol. 37, # 6 p. 375 - 376
143-66-8
+
589-15-1
对溴溴苄
→
反应条件
2116-36-1
反应条件
C60H48Cl2FeP4; Zn(C6H4-4-OMe)2 in tetrahydrofuran; toluene T=85°C; Suzuki coupling; 4 h; Inert atmosphere;
参考文献
Bedford, Robin B.; Hall, Mark A.; Hodges, George R.; Huwe, Michael; Wilkinson, Mark C.
Chemical Communications, 2009 , # 42 p. 6430 - 6432
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