1: methanol / 10 h / Heating
2: polyphosphoric acid / 3 h / 120 °C
3: quinoline / 1 h / 230 °C
View Scheme
参考文献
Iwanowicz, Edwin J.; Lau, Wan F.; Lin, James; Roberts, Daniel G. M.; Seiler, Steven M.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 12 p. 1339 - 1344
sulfuric acid in 1,4-dioxane
T=60°C; Fischer indole synthesis; 2 h;
参考文献
Kalin, Jay H.; Butler, Kyle V.; Akimova, Tatiana; Hancock, Wayne W.; Kozikowski, Alan P.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 2 p. 639 - 651