间溴苯胺合成路线

参考文献

Leahy, James W.; Buhr, Chris A.; Johnson, Henry W. B.; Kim, Byung Gyu; Baik, Taegon; Cannoy, Jonah; Forsyth, Timothy P.; Jeong, Joon Won; Lee, Matthew S.; Ma, Sunghoon; Noson, Kevin; Wang, Longcheng; Williams, Matthew; Nuss, John M.; Brooks, Eric; Foster, Paul; Goon, Leanne; Heald, Nathan; Holst, Charles; Jaeger, Christopher; Lam, Scott; Lougheed, Julie; Nguyen, Lam; Plonowski, Arthur; Song, Joanne; Stout, Thomas; Wu, Xiang; Yakes, Michael F.; Yu, Peiwen; Zhang, Wentao; Lamb, Peter; Raeber, Olivia
Journal of Medicinal Chemistry, 2012 , vol. 55, # 11 p. 5467 - 5482

591-19-5间溴苯胺

13140-73-3

参考文献

Lal, Samridhi; Snape, Timothy J.
RSC Advances, 2014 , vol. 4, # 4 p. 1609 - 1615

591-19-5间溴苯胺+

103-80-0氯化苯乙酰

13140-73-3

参考文献

Suzuki, Takayoshi; Khan, Mohammed Naseer Ahmed; Sawada, Hideyuki; Imai, Erika; Itoh, Yukihiro; Yamatsuta, Katsura; Tokuda, Natsuko; Takeuchi, Jun; Seko, Takuya; Nakagawa, Hidehiko; Miyata, Naoki
Journal of Medicinal Chemistry, 2012 , vol. 55, # 12 p. 5760 - 5773

591-19-5间溴苯胺+

175357-98-94-氯-6-氟吡啶并[3,4-D]嘧啶

171179-03-6N-(3-溴苯基)-6-氟-吡啶并[3,4-d]嘧啶-4-胺

参考文献

Rewcastle, Gordon W.; Murray, Donna K.; Elliott, William L.; Fry, David W.; Howard, Curtis T.; Nelson, James M.; Roberts, Billy J.; Vincent, Patrick W.; Hollis Showalter; Thomas Winters; Denny, William A.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 5 p. 742 - 751

67-63-0异丙醇+

591-19-5间溴苯胺+

175357-98-94-氯-6-氟吡啶并[3,4-D]嘧啶

171179-03-6N-(3-溴苯基)-6-氟-吡啶并[3,4-d]嘧啶-4-胺

参考文献

Warner-Lambert Company
Patent: US6313292 B1, 2001 ;
US 6313292 B1

77-78-1硫酸二甲酯+

591-19-5间溴苯胺

16518-62-03-溴-N,N-二甲基苯胺

参考文献

Nair, Haridasan K.; Lee, Keun; Quinn, Daniel M.
Journal of the American Chemical Society, 1993 , vol. 115, # 22 p. 9939 - 9941

591-19-5间溴苯胺