(6CI,7CI)-2-对甲苯萘合成路线 （共 62 条）
反应条件
CuF2; Ni(PCy3)2Cl2; potassium tert-butylate; tri-cyclo-hexyl-phosphine in 1,4-dioxane
T=110°C; Suzuki-Miyaura coupling; 20 h; Inert atmosphere;
参考文献
Yu, Da-Gang; Yu, Miao; Guan, Bing-Tao; Li, Bi-Jie; Zheng, Yang; Wu, Zhen-Hua; Shi, Zhang-Jie
Organic Letters, 2009 , vol. 11, # 15 p. 3374 - 3377
反应条件
Cp2Ni; triethyl borane; potassium tert-butylate in tetrahydrofuran
T=80°C; 12 h; Inert atmosphere;
参考文献
Kobayashi, Osamu; Uraguchi, Daisuke; Yamakawa, Tetsu
Organic Letters, 2009 , vol. 11, # 12 p. 2679 - 2682
反应条件
potassium phosphate; Ni(PCy3)2Cl2 in 1,4-dioxane
T=110°C; Suzuki-Miyaura coupling; 24 h; Inert atmosphere;
参考文献
Chen, Hu; Huang, Zhongbin; Hu, Xiaoming; Tang, Guo; Xu, Pengxiang; Zhao, Yufen; Cheng, Chien-Hong
Journal of Organic Chemistry, 2011 , vol. 76, # 7 p. 2338 - 2344
反应条件
1,2,3-Benzotriazole; palladium diacetate; potassium carbonate in water; N,N-dimethyl-formamide
T=80°C; Suzuki-Miyaura coupling;
参考文献
Jha, Rajeev Ranjan; Chaudhary, Ritu; Chandra, Ramesh; Verma, Akhilesh Kumar
Journal of the Indian Chemical Society, 2011 , vol. 88, # 8 p. 1187 - 1194
反应条件
tetrabutyl ammonium fluoride; potassium carbonate in water
T=100°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Yamada, Yoichi M. A.; Sarkar, Shaheen M.; Uozumi, Yasuhiro
Journal of the American Chemical Society, 2012 , vol. 134, # 6 p. 3190 - 3198
反应条件
1: 1-(iodo)-4-methylbenzene With methyllithium; zinc(II) chloride in tetrahydrofuran; diethyl ether
T=-78°C; 2 h;
2: beta-naphthyl methyl ether With bis(1,5-cyclooctadiene)nickel (0); tri-cyclo-hexyl-phosphine in toluene
T=20°C; Negishi coupling reaction; 12 h; Inert atmosphere;
参考文献
Wang, Chao; Ozaki, Takashi; Takita, Ryo; Uchiyama, Masanobu
Chemistry - A European Journal, 2012 , vol. 18, # 12 p. 3482 - 3485
反应条件
[NiCl2(PMe3)2] in tetrahydrofuran
T=25°C; 12 h; Inert atmosphere;
参考文献
Liu, Ning; Wang, Zhong-Xia
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1641 - 1645
反应条件
1: RLi or RMgBr, R = 4-MeC6H4 With indium(III) chloride in tetrahydrofuran
T=-78°C; 0.5 h; Inert atmosphere;
2: C10H7-2-OTs With Ni(PCy3)2Cl2; tri-cyclo-hexyl-phosphine in tetrahydrofuran
T=20 - 80°C; Inert atmosphere;
参考文献
Zhang, Liang; Luo, Yong; Wu, Jie
Synlett, 2010 , # 12 p. 1845 - 1848
反应条件
Ni(PCy3)2Cl2 in toluene
T=30°C; Kumada-Tamao-Corriu coupling; 1 h; Inert atmosphere;
参考文献
Zhao, Fei; Yu, Da-Gang; Zhu, Ru-Yi; Xi, Zhenfeng; Shi, Zhang-Jie
Chemistry Letters, 2011 , vol. 40, # 9 p. 1001 - 1003
反应条件
1,1'-bis(diphenylphosphanyl)ferrocenenickel(II) chloride in tetrahydrofuran; diethyl ether
24 h; Heating;
参考文献
Cho, Chul-Hee; Yun, Hee-Sung; Park, Kwangyong
Journal of Organic Chemistry, 2003 , vol. 68, # 8 p. 3017 - 3025
