in methanol; ethanol; chloroform 3 h; Ambient temperature;

1: 1.) NaH / 1.) DMF, oil, 2-5 deg C, 15 min, 2.) DMF, oil, 2-5 deg C, 2 h 2: 97 percent / 20percent HBr / acetic acid / 1 h / Ambient temperature 3: 89 percent / hexamethylphosphoric acid triamide / 5 h 4: 91.5 percent / KI / acetone / 1 h / Heating 5: 100 percent / ethanol; CHCl3; methanol / 3 h / Ambient temperature View Scheme

1: 91.5 percent / KI / acetone / 1 h / Heating 2: 100 percent / ethanol; CHCl3; methanol / 3 h / Ambient temperature View Scheme

1: 97 percent / 20percent HBr / acetic acid / 1 h / Ambient temperature 2: 89 percent / hexamethylphosphoric acid triamide / 5 h 3: 91.5 percent / KI / acetone / 1 h / Heating 4: 100 percent / ethanol; CHCl3; methanol / 3 h / Ambient temperature View Scheme

1: 89 percent / hexamethylphosphoric acid triamide / 5 h 2: 91.5 percent / KI / acetone / 1 h / Heating 3: 100 percent / ethanol; CHCl3; methanol / 3 h / Ambient temperature View Scheme