2-氨基四氢苯并噻吩-3-甲酸合成路线 （共 5 条）
反应条件
oxalic acid in isopropyl alcohol T=35°C; 0.5 h; Inert atmosphere;
参考文献
F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; BUETTELMANN, Bernd; CECCARELLI, Simona M.; KUEHNE, Holger; KUHN, Bernd; NEIDHART, Werner; OBST SANDER, Ulrike; RICHTER, Hans
Patent: WO2013/189841 A1, 2013 ;
Location in patent: Page/Page column 248; 249 ;
反应条件
sodium hydroxide in ethanol
5 h; Heating;
参考文献
Kanwar, Seema; Sharma
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 11 p. 2367 - 2371
反应条件
1: sulfur / Heating
2: water; sodium hydroxide
View Scheme
参考文献
Abdalha; El-Kassaby, M.K. Abou; El-Regal; Ali
Synthetic Communications, 2011 , vol. 41, # 19 p. 2811 - 2821
反应条件
1: pyridine / 1 h / Cooling with ice
2: acetic anhydride / 5 h / Heating
View Scheme
参考文献
Abdalha; El-Kassaby, M.K. Abou; El-Regal; Ali
Synthetic Communications, 2011 , vol. 41, # 19 p. 2811 - 2821
反应条件
pyridine
1 h; Cooling with ice;
参考文献
Abdalha; El-Kassaby, M.K. Abou; El-Regal; Ali
Synthetic Communications, 2011 , vol. 41, # 19 p. 2811 - 2821
