乙基(2E)-3-(3-吡啶基)丙烯酸酯合成路线 （共 37 条）
反应条件
1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride in tetrahydrofuran T=-40 - 20°C; 2: pyridine-3-aldehyde in tetrahydrofuran T=20°C;
参考文献
Welter, Carolin; Moreno, Rosa M.; Streiff, Stephane; Helmchen, Guenter
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 18 p. 3266 - 3268
反应条件
[PdCl{[(η5-C5H5)]Fe[(η5-C5H3)CH=NCy]}(PCy3)]; triethylamine in N,N-dimethyl-formamide T=140°C; Heck reaction; 16 h;
参考文献
Xu, Chen; Gong, Jun-Fang; Yue, Su-Fang; Zhu, Yu; Wu, Yang-Jie
Dalton Transactions, 2006 , # 39 p. 4730 - 4739
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 16 h;
参考文献
Le Notre, Jerome; Firet, Judith J.; Sliedregt, Leo A. J. M.; Van Steen, Bart J.; Van Koten, Gerard; Gebbink, Robertus J. M. Klein
Organic Letters, 2005 , vol. 7, # 3 p. 363 - 366
反应条件
hydrogenchloride in ethanol; ethyl acetate
反应条件
sulfuric acid in ethanol 19 h; Heating;
参考文献
Weller, Dwight D.; Stirchak, Eugene P.; Weller, Doreen L.
Journal of Organic Chemistry, 1983 , vol. 48, # 24 p. 4597 - 4605
反应条件
tetra-n-butylammonium acetate in dichloromethane T=0°C; 1 h;
参考文献
Michida, Makoto; Mukaiyama, Teruaki
Chemistry Letters, 2008 , vol. 37, # 7 p. 704 - 705
反应条件
piperidine in dichloromethane T=20°C; 5 h; stereoselective reaction;
参考文献
China Raju, Bhimapaka; Suman, Pathi
Chemistry - A European Journal, 2010 , vol. 16, # 39 p. 11840 - 11842
反应条件
poly{styrene-co-[4-(N-methyl-N-vinylbenzyl-amino)pyridine]-co-[1-phenyl-3-(4-vinylbenzyl)piperazine]} in N,N-dimethyl-formamide T=50°C; decarboxylative Doebner-Knoevenagel condensation reaction; optical yield given as percent destereoselective reaction;
参考文献
Lu, Jinni; Toy, Patrick H.
Synlett, 2011 , # 12 p. 1723 - 1726
反应条件
in acetonitrile T=20°C; Wittig reaction;
参考文献
Lewandowska, Elzbieta; Chatfield, David C.
European Journal of Organic Chemistry, 2005 , # 15 p. 3297 - 3303
反应条件
in tetrahydrofuran T=70°C; 40 h; Inert atmosphere; optical yield given as percent destereoselective reaction;
参考文献
Shao, You-Dong; Wu, Xue-Song; Tian, Shi-Kai
European Journal of Organic Chemistry, 2012 , # 8 p. 1590 - 1596
