1: (6-chloro-pyridazine-3-yl)-hydrazine; 1-[(benzyloxy)carbonyl]-3-piperidinecarboxylic acid With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; 16 h; 2: With acetic acid T=110°C; 48 h; 3: piperidine With hydrogen; palladium 10 on activated carbon more than 3 stages;