(R)-(-)-2-辛醇合成路线 （共 140 条）
反应条件
diethylamino-sulfur trifluoride in dichloromethane variously O-substituted derivatives were also studied; Product distribution;
参考文献
Tetrahedron, , vol. 51, # 32 p. 8771 - 8782
反应条件
triphenylphosphine in tetrahydrofuran; water
参考文献
University Research Corporation
Patent: US5543078 A1, 1996 ;
反应条件
(i) 1-methyl-2-fluoropyridinium tosylate, LiN3, Et3N, CHCl3, HMPA, (ii) LiAlH4, Et2O; Multistep reaction;
参考文献
Inoue, Yoshio; Taguchi, Masaaki; Hashimoto, Harukichi
Synthesis, 1986 , # 4 p. 332 - 334
反应条件
Yarrowia lipolytica short chain dehydrogenase/reductase; nicotinamide adenine dinucleotide phosphate; magnesium chloride in aq. buffer T=28°C; pH=8.0; 0.166667 h; Enzymatic reaction;
参考文献
Yang, Yi; Liu, Ji; Li, Zhi
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3120 - 3124
Angew. Chem., 2014 , vol. 126, # 12 p. 3348,1
反应条件
1.1: pyridine / CH2Cl2 / 0.17 h / 20 °C 1.2: 100 percent / CH2Cl2 / 2.5 h / 20 °C 2.1: 46 percent / aq. H2SO4 / tetrahydrofuran / 19 h / Heating View Scheme
参考文献
Voss, Constance V.; Gruber, Christian C.; Kroutil, Wolfgang
Angewandte Chemie - International Edition, 2008 , vol. 47, # 4 p. 741 - 745
反应条件
hydroxide; triphenylphosphine; diethylazodicarboxylate 1.) THF, - 30 deg C; ee(S) : 65percent; Multistep reaction. Title compound not separated from byproducts;
参考文献
Cabaret, Daniel; Maigrot, Nicole; Welvart, Zoltan
Tetrahedron Letters, 1981 , vol. 22, # 52 p. 5279 - 5282
反应条件
hydrogenchloride T=100°C; dextrorotatory form of 2-chloro-octane;
参考文献
Pickard; Kenyon
Journal of the Chemical Society, 1911 , vol. 99, p. 55,71
Journal of the Chemical Society, 1914 , vol. 105, p. 1121,1123, 1128
反应条件
1: triethylamine / 20 °C / Inert atmosphere 2: anhydrous iron chloride / dichloromethane / 0.08 h / 20 °C / Inert atmosphere View Scheme
参考文献
Ortega, Nuria; Feher-Voelger, Andres; Brovetto, Margarita; Padron, Juan I.; Martin, Victor S.; Martin, Tomas
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 6 p. 963 - 972
反应条件
tetrachloromethane in acetonitrile 3 h; Heatingracemization; Thermodynamic data;
参考文献
Slagle, J. D.; Huang, T. T.-S.; Franzus, B.
Journal of Organic Chemistry, 1981 , vol. 46, # 17 p. 3526 - 3530
反应条件
diethylamino-sulfur trifluoride in dichloromethane variously O-substituted derivatives were also studied; Product distribution;
参考文献
Matsumura, Yasushi; Shimada, Toyomichi; Nakayama, Toshiaki; Urushihara, Masahiro; Asai, Tomoyuki; et al.
Tetrahedron, 1995 , vol. 51, # 32 p. 8771 - 8782
