(R)-(-)-2-辛醇合成路线 （共 140 条）
反应条件
1: dioxane / 20 h / 100 °C 2: 90 percent / 30 percent NaOMe / methanol / 12 h View Scheme
参考文献
Angewandte Chemie, , vol. 99, # 8 p. 800 - 802
反应条件
Candida antarctica lipase B; sodium carbonate in i-Pr2O Inert atmosphereEnzymatic reaction; optical yield given as percent ee;
参考文献
Jalalian, Nazli; Olofsson, Berit
Tetrahedron, 2010 , vol. 66, # 31 p. 5793 - 5800
反应条件
NADPH; P450 BM3 mutation of F87V/A328F enzyme in dimethyl sulfoxide pH=7.5; aq. phosphate bufferEnzymatic reaction; optical yield given as percent eeregioselective reaction;
参考文献
Chemical Communications, , vol. 47, # 3 p. 944 - 946
反应条件
complex from (4R,5R)-2,2-dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane and tris(isopropoxy)chlorotitane in tetrahydrofuran T=-50°C; Yield given. Yields of byproduct given;
参考文献
Helvetica Chimica Acta, , vol. 70, p. 954 - 974
反应条件
sodium hydroxide T=25°C; 4 h;
参考文献
Journal of Organic Chemistry, , vol. 53, # 23 p. 5531 - 5534
反应条件
Pseudomonas cepacia lipase in di-isopropyl ether T=30°C; Esterification; Racemate separation; 16 h;
参考文献
Synlett, , # 2 p. 225 - 226
反应条件
1: dimethylformamide; hexamethylphosphoric acid triamide / 16 h / 55 °C 2: 100 percent / LiAlH4 / tetrahydrofuran 3: 56 percent / pyridine 4: 95 percent / LiAlH4 / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 199 - 202
反应条件
1: [RuCl2(p-cumene)]2; sodium carbonate; trifuran-2-yl-phosphane / toluene / 50 °C / |Inert atmosphere; |Schlenk technique 2: hydrogen; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; C51H35NO2P2 / dichloromethane / 1 h / 0 °C / |Schlenk technique; |Inert atmosphere; |Autoclave 3: potassium hydroxide / methanol / 18 h / 20 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Chemistry - A European Journal, , vol. 19, # 40 p. 13299 - 13303
反应条件
1: hydrogen; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; C51H35NO2P2 / dichloromethane / 1 h / 0 °C / |Schlenk technique; |Inert atmosphere; |Autoclave 2: potassium hydroxide / methanol / 18 h / 20 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Chemistry - A European Journal, , vol. 19, # 40 p. 13299 - 13303
反应条件
D-glucopyranose in aq. phosphate buffer; dimethyl sulfoxide T=30°C; pH=8; 4 h; Reagent/catalyst; enantioselective reaction;
参考文献
Angewandte Chemie - International Edition, , vol. 53, # 12 p. 3120 - 3124
Angew. Chem., , vol. 126, # 12 p. 3348,1
