2-甲基-1,3-二噻烷合成路线 （共 22 条）
反应条件
boron trifluoride diethyl etherate in dichloromethane T=0°C; 1 h;
参考文献
European Journal of Organic Chemistry, , # 14 p. 2687 - 2695
反应条件
sodium amide; diethylene glycol monoethyl ether, sodium salt in ethylene glycol dimethyl ether T=0°C; 0.2 h;
参考文献
Tetrahedron, , vol. 52, # 48 p. 15147 - 15156
反应条件
potassium hydride in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide T=25°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 45, # 12 p. 2460 - 2468
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=-15°C; 1 h; Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 37, # 23 p. 4069 - 4079
反应条件
in diethyl ether 1 h; Heating;
参考文献
Chemische Berichte, , vol. 118, # 5 p. 1798 - 1808
反应条件
boron trifluoride diethyl etherate; NAF 1) CH2Cl2, 0 deg C; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 27, # 52 p. 6305 - 6306
反应条件
1: 2-methyl-[1,3]dithiane With n-butyllithium in tetrahydrofuran; hexane T=20 - 25°C; 2: 2-(butylthiomethyl)-1,3-dithiane in tetrahydrofuran; hexane T=20°C; 3: benzaldehyde in tetrahydrofuran; hexane T=20°C; 3 h; Further stages.;
参考文献
Valiulin, Roman A.; Halliburton, Logan M.; Kutateladze, Andrei G.
Organic Letters, 2007 , vol. 9, # 20 p. 4061 - 4063
反应条件
1: 2-methyl-[1,3]dithiane With n-butyllithium in tetrahydrofuran; hexane T=20 - 25°C; 2: 2-(butylthiomethyl)-1,3-dithiane in tetrahydrofuran; hexane T=20°C; 3: propionaldehyde in tetrahydrofuran; hexane T=20°C; 3 h; Further stages.;
参考文献
Valiulin, Roman A.; Halliburton, Logan M.; Kutateladze, Andrei G.
Organic Letters, 2007 , vol. 9, # 20 p. 4061 - 4063
反应条件
n-butyllithium in tetrahydrofuran T=-78 - -10°C; 2 h;
参考文献
Dress; Roelle; Wenzel; Boesherz; Frommknecht; Merkel; Sauer
Zeitschrift fur Physikalische Chemie, 2001 , vol. 215, # 1 p. 77 - 90
反应条件
in tetrahydrofuran; hexane T=-30°C; 1 h;
参考文献
Tacke, Reinhold; Fritsche, Kirsten; Tafel, Andrea; Wuttke, Frank
Journal of Organometallic Chemistry, 1990 , vol. 388, # 1+2 p. 47 - 55
