1,1'-联-2-萘酚合成路线 （共 233 条）
反应条件
1: 1,1'-binaphthyl-2,2'-diol With sodium hydride in tetrahydrofuran T=0 - 20°C; 2: chloromethyl methyl ether in tetrahydrofuran T=20°C; 4.5 h;
参考文献
Wu, T. Robert; Shen, Lixin; Chong, J. Michael
Organic Letters, 2004 , vol. 6, # 16 p. 2701 - 2704
反应条件
1: 1,1'-binaphthyl-2,2'-diol With sodium hydride in tetrahydrofuran; mineral oil T=0°C; 1 h; Inert atmosphere; 2: methoxymethoxy chloride in tetrahydrofuran; mineral oil T=0 - 20°C; 4.5 h; Inert atmosphere;
参考文献
Lv, Na; Xie, Meilan; Gu, Weibing; Ruan, Huanyang; Qiu, Song; Zhou, Chunshan; Cui, Zheng
Organic Letters, 2013 , vol. 15, # 10 p. 2382 - 2385
反应条件
1: With copper(l) chloride; (-)-sparteine in methanol; dichloromethane T=25°C; 24 h; Inert atmosphereDarkness; 2: With hydrogenchloride in methanol; dichloromethane; water optical yield given as percent eeenantioselective reaction;
参考文献
Hu, Gang; Holmes, Daniel; Gendhar, Brina Fay; Wulff, William D.
Journal of the American Chemical Society, 2009 , vol. 131, # 40 p. 14355 - 14364
反应条件
1: With copper(l) chloride; (-)-sparteine in methanol; dichloromethane T=25°C; 24 h; Inert atmosphereDarkness; 2: With sodium hydrogencarbonate in methanol; dichloromethane; water optical yield given as percent eeenantioselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 131, # 40 p. 14355 - 14364
反应条件
(8S,9R)-(-)-N-benzyl-cinchonidinium chloride in acetonitrile resolution of racemate; 4 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 65, # 20 p. 6319 - 6337
反应条件
Pseudomonas sp. lipoprotein lipase in isopropyl alcohol; acetone T=40°C; 120 h;
参考文献
Juarez-Hernandez, Marcela; Johnson, Dean V.; Holland, Herbert L.; McNulty, James; Capretta, Alfredo
Tetrahedron Asymmetry, 2003 , vol. 14, # 3 p. 289 - 291
反应条件
1: in methanol T=50°C; 1 h; 2: With hydrogenchloride in water; ethyl acetate Product distribution / selectivity;
参考文献
LUPIN LIMITED; ROY, Bhairab, Nath; SINGH, Girij, Pal; LATHI, Piyush, Suresh; MITRA, Rangan
Patent: WO2011/86566 A1, 2011 ;
Location in patent: Page/Page column 30-31 ;
反应条件
1: in methanol T=50°C; 1 h; 2: With hydrogenchloride in water; ethyl acetate Product distribution / selectivity;
参考文献
LUPIN LIMITED; ROY, Bhairab, Nath; SINGH, Girij, Pal; LATHI, Piyush, Suresh; MITRA, Rangan
Patent: WO2011/86566 A1, 2011 ;
Location in patent: Page/Page column 31 ;
反应条件
boric acid in tetrahydrofuran 6 h; Heatingresolution of racemate;
参考文献
Helvetica Chimica Acta, , vol. 86, # 1 p. 157 - 163
反应条件
C42H60N6O7 in toluene T=0°C; 24 h;
参考文献
Mueller, Christian E.; Zell, Daniela; Hrdina, Radim; Wende, Raffael C.; Wanka, Lukas; Schuler, Soeren M. M.; Schreiner, Peter R.
Journal of Organic Chemistry, 2013 , vol. 78, # 17 p. 8465 - 8484
