2-氰基-3-甲基-丁二酸二乙酯合成路线 （共 12 条）
参考文献
Linstead et al.
Journal of the Chemical Society, 1937 , p. 911,917
Full Text Show Details
Jeffery; Vogel
Journal of the Chemical Society, 1948 , p. 663
Full Text Show Details
Qudrat-i-Khuda; Ghosh
Journal of the Indian Chemical Society, 1940 , vol. 17, p. 19,24
参考文献
Bone; Sprankling
Journal of the Chemical Society, 1899 , vol. 75, p. 860
反应条件
1: hydrochloric acid / 25 °C 2: water View Scheme
参考文献
Fischer,E.; Flatau
Justus Liebigs Annalen der Chemie, 1909 , vol. 365, p. 14 Anm.
反应条件
cyanoacetic acid ethyl ester; triphenylphosphine in tetrahydrofuran
24 h; Ambient temperature;
参考文献
Kurihara, Toshio; Sugizaki, Masaru; Kime, Itaru; Wada, Makoto; Mitsunobu, Oyo
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 7 p. 2107 - 2112
反应条件
2,6-di-tert-butyl-phenol; triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran
24 h; Ambient temperature;
参考文献
Kurihara, Toshio; Sugizaki, Masaru; Kime, Itaru; Wada, Makoto; Mitsunobu, Oyo
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 7 p. 2107 - 2112
反应条件
ethanol
levorotatory α-methyl-α'-cyano-succinic acid diethyl ester;
参考文献
Fischer,E.; Flatau
Justus Liebigs Annalen der Chemie, 1909 , vol. 365, p. 14 Anm.
参考文献
Bone; Sprankling
Journal of the Chemical Society, 1899 , vol. 75, p. 860
Full Text Show Details
Barthe
Annales de Chimie (Cachan, France), 1892 , vol. <6>27, p. 269
参考文献
Linstead et al.
Journal of the Chemical Society, 1937 , p. 911,917
Full Text Show Details
Jeffery; Vogel
Journal of the Chemical Society, 1948 , p. 663
Full Text Show Details
Qudrat-i-Khuda; Ghosh
Journal of the Indian Chemical Society, 1940 , vol. 17, p. 19,24
反应条件
1: concentrated hydrochloric acid
2: concentrated H2SO4
3: sodium; ethanol
4: HBr / 140 - 145 °C
5: benzene
View Scheme
参考文献
Qudrat-i-Khuda; Ghosh
Journal of the Indian Chemical Society, 1940 , vol. 17, p. 19,24
反应条件
hydrogenchloride
T=25°C; levorotatory propane-α.α.β-tricarboxylic acid;
参考文献
Fischer,E.; Flatau
Justus Liebigs Annalen der Chemie, 1909 , vol. 365, p. 14 Anm.
