2,2-二乙氧基乙酸乙酯合成路线 （共 88 条）
反应条件
1: With sodium hydroxide in ethanol
1 h; Reflux;
2: With thionyl chloride in diethyl ether
T=0°C; Reflux;
参考文献
Babaev; Nevskaya; Dlinnykh; Rybakov
Chemistry of Heterocyclic Compounds, 2009 , vol. 45, # 1 p. 93 - 104
反应条件
sodium hydride
T=20°C; 6 h;
参考文献
Compton, Dennis R.; Carlson, Kathryn E.; Katzenellenbogen, John A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 22 p. 5681 - 5684
反应条件
in diethyl ether
17 h;
参考文献
Balsevich, J.
Canadian Journal of Chemistry, 1983 , vol. 61, p. 1053 - 1059
反应条件
1: NaH / benzene / 0 °C
2: aq. NaOH
View Scheme
参考文献
Adams, Jerry L.; Boehm, Jeffrey C.; Kassis, Shouki; Gorycki, Peter D.; Webb, Edward F.; Hall, Ralph; Sorenson, Margaret; Lee, John C.; Ayrton, Andrew; Griswold, Don E.; Gallagher, Timothy F.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 22 p. 3111 - 3116
反应条件
boron trifluoride diethyl etherate in chloroform
0.5 h; Inert atmosphereReflux;
参考文献
Makino, Kazuishi; Goto, Takayuki; Hiroki, Yasuhiro; Hamada, Yasumasa
Tetrahedron Asymmetry, 2008 , vol. 19, # 24 p. 2816 - 2828
反应条件
2: diethyl ether / man zersetzt das Reaktionsprodukt mit Eis und Salmiakloesung
View Scheme
参考文献
Dakin; Dudley
Journal of the Chemical Society, 1914 , vol. 105, p. 2458
参考文献
Mylo
Chemische Berichte, 1911 , vol. 44, p. 3214
反应条件
1: NH3 / H2O
2: LiAlH4 / tetrahydrofuran / Heating
3: toluene / Heating
View Scheme
参考文献
Bouvier,P. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 271 - 278
反应条件
1: NH3 / H2O
2: LiAlH4 / tetrahydrofuran / Heating
3: toluene / Heating
View Scheme
参考文献
Bouvier,P. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 271 - 278
反应条件
1: NH3 / H2O
2: LiAlH4 / tetrahydrofuran / Heating
3: toluene / Heating
View Scheme
参考文献
Bouvier,P. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 271 - 278
