甲基丙二酸二乙酯合成路线

参考文献

Beckwith, Athelstan L. J.; Easton, Christopher J.; Lawrence, Tony; Serelis, Algirdas K.
Australian Journal of Chemistry, 1983 , vol. 36, # 3 p. 545 - 556

50-00-0甲醛+

107-05-1氯丙烯+

609-08-5甲基丙二酸二乙酯

5331-70-4

参考文献

Brettle,R.; Holland,F.S.
Journal of the Chemical Society, 1962 , p. 4836 - 4839

参考文献

Steele
Journal of the American Chemical Society, 1931 , vol. 53, p. 286

参考文献

Jinsheng, Li; Pritzkow, Wilhelm; Voerckel, Volkmar
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1994 , vol. 336, # 1 p. 43 - 52

108-94-1环己酮+

609-08-5甲基丙二酸二乙酯

52263-19-1Alpha-甲基-(3-氧代环己基)丙二酸二乙酯

参考文献

Hoffmann-La Roche Inc.
Patent: US4264500 A1, 1981 ;

27129-86-83,5-二甲基苄基溴+

609-08-5甲基丙二酸二乙酯

52528-74-2

参考文献

John, T. K.; Angadi, V. B.; Rao, Krishna G. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 8 p. 735 - 737

579-49-74-氟苯基-2-噻吩酮+

609-08-5甲基丙二酸二乙酯

52779-57-4甲基[4-(2-噻吩基羰基)苯基]丙二酸二乙酯

参考文献

Janssen Pharmaceutica N.V.
Patent: US4035376 A1, 1977 ;

5329-33-9O-甲基异脲盐酸盐+

609-08-5甲基丙二酸二乙酯

62091-86-5

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; EBEL, Heiner; FRATTINI, Sara; GERLACH, Kai; GIOVANNINI, Riccardo; HOENKE, Christoph; MAZZAFERRO, Rocco; SANTAGOSTINO, Marco; SCHEUERER, Stefan; TAUTERMANN, Christofer; TRIESELMANN, Thomas
Patent: WO2011/73154 A1, 2011 ;
Location in patent: Page/Page column 87; 88 ;
WO 2011/073154 A1

29427-58-5o-甲基异尿素硫酸氢盐+

609-08-5甲基丙二酸二乙酯

62091-86-5

参考文献

Proskelia SAS
Patent: US2008/58348 A1, 2008 ;
Location in patent: Page/Page column 24 ;

62091-86-5

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; EBEL, Heiner; FRATTINI, Sara; GIOVANNINI, Riccardo; SCHEUERER, Stefan
Patent: WO2012/171863 A1, 2012 ;
Location in patent: Page/Page column 87 ;
WO 2012/171863 A1