2-氯乙酰乙酸乙酯合成路线

67-66-3氯仿

609-15-42-氯乙酰乙酸乙酯

参考文献

Justus Liebigs Annalen der Chemie, vol. 253, p. 171

2049-86-72,3-二乙酰基丁二酸二乙酯

参考文献

American Chemical Journal, , vol. 32, p. 468

1072-98-62-氨基-5-氯吡啶+

609-15-42-氯乙酰乙酸乙酯

330858-13-46-氯-2-甲基H-咪唑并[1,2-a]吡啶-3-羧酸乙酯

参考文献

Moraski, Garrett C.; Markley, Lowell D.; Cramer, Jeffrey; Hipskind, Philip A.; Boshoff, Helena; Bailey, Mai A.; Alling, Torey; Ollinger, Juliane; Parish, Tanya; Miller, Marvin J.
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 7 p. 675 - 679

2227-79-4硫代苯甲酰胺+

609-15-42-氯乙酰乙酸乙酯

53715-64-34-甲基-2-苯基-1,3-噻唑-5-甲酸乙酯

参考文献

Yavari, Issa; Sayyed-Alangi, S. Zahra; Hajinasiri, Rahimeh; Sajjadi-Ghotbabadi, Hadi
Monatshefte fur Chemie, 2009 , vol. 140, # 2 p. 209 - 211

2227-79-4硫代苯甲酰胺+

609-15-42-氯乙酰乙酸乙酯

33763-20-14-甲基-2-苯基噻唑-5-羧酸

参考文献

Hubacher
Justus Liebigs Annalen der Chemie, 1890 , vol. 259, p. 234

507-09-5硫代乙酸+

609-15-42-氯乙酰乙酸乙酯

317319-35-02-[2-氟-4-(三氟甲基)苯基]-4-甲基-1,3-噻唑-5-羧酸乙酯

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2003/74504 A2, 2003 ;
Location in patent: Page/Page column 34-35 ;

317319-34-92-氟-4-三氟甲基硫代苯甲酰胺+

609-15-42-氯乙酰乙酸乙酯

317319-35-02-[2-氟-4-(三氟甲基)苯基]-4-甲基-1,3-噻唑-5-羧酸乙酯

参考文献

Brown, Andrew D.; Davis, Roman D.; Fitzgerald, Russ N.; Glover, Bobby N.; Harvey, Kim A.; Jones, Lynda A.; Liu, Bing; Patterson, Daniel E.; Sharp, Matthew J.
Organic Process Research and Development, 2009 , vol. 13, # 2 p. 297 - 302

609-15-42-氯乙酰乙酸乙酯

317319-21-4乙基2-[3-氟-(三氟甲基)苯基]-4-甲基-噻唑-5-羧酸酯

参考文献

Sznaidman, Marcos L.; Haffner, Curt D.; Maloney, Patrick R.; Fivush, Adam; Chao, Esther; Goreham, Donna; Sierra, Michael L.; LeGrumelec, Christelle; Xu, H. Eric; Montana, Valerie G.; Lambert, Millard H.; Willson, Timothy M.; Oliver Jr., William R.; Sternbach, Daniel D.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 9 p. 1517 - 1521

4621-66-3巯基尼古胺+

609-15-42-氯乙酰乙酸乙酯

39091-00-44-甲基-2-(3-吡啶)-1,3-噻唑-5-羧酸乙酯

参考文献

Ronkin, Steven M.; Badia, Michael; Bellon, Steve; Grillot, Anne-Laure; Gross, Christian H.; Grossman, Trudy H.; Mani, Nagraj; Parsons, Jonathan D.; Stamos, Dean; Trudeau, Martin; Wei, Yunyi; Charifson, Paul S.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 9 p. 2828 - 2831

95-54-51,2-苯二胺+

609-15-42-氯乙酰乙酸乙酯

3885-38-9乙基3-甲基-2-喹喔啉羧酸酯

参考文献

Meshram; Ramesh; Santosh Kumar; Chennakesava Reddy
Tetrahedron Letters, 2010 , vol. 51, # 33 p. 4313 - 4316