2-甲基-1-苯基-1-丙醇合成路线 （共 136 条）
反应条件
tertiary amine-based nucleophilic catalyst in 1,1-dimethylpropan-1-ol
T=0°C; 17 h;
参考文献
Jeong, Kyu-Sung; Kim, Soong-Hyun; Park, Hyun-Jin; Chang, Kyoung-Jin; Kwan, Soo Kim
Chemistry Letters, 2002 , # 11 p. 1114 - 1115
反应条件
hexamethyl-silane; pyridinium hydrobromide perbromide in chloroform
T=25°C; 0.5 h;
参考文献
Olah, George A.; Gupta, B. G. Balaram; Malhotra, Ripudaman; Narang, Subhash C.
Journal of Organic Chemistry, 1980 , vol. 45, # 9 p. 1638 - 1639
反应条件
1: KHSO4 / 3 h / 120 - 130 °C
2: 1) Br2, 2) KOH / 1) CHCl3, 2) EtOH, 2 h, reflux
View Scheme
参考文献
Knorr, Rudolf; Lattke, Ernst
Chemische Berichte, 1981 , vol. 114, # 6 p. 2116 - 2131
反应条件
1: 81 percent / PBr3, pyridine / diethyl ether / 2.5 h / Ambient temperature
2: 86 percent / EtONa / ethanol / 1.) 10 min, 2.) reflux, 12 h
3: 73 percent / KOH, H2O / ethanol / 3 h / Heating
4: 75 percent / 0.33 h / 180 - 185 °C
View Scheme
参考文献
Maguire, Anita R.; Buckley, N. Rachael; O'Leary, Patrick; Ferguson, George
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 24 p. 4077 - 4091
反应条件
T=25 - 30°C; Product distribution;
参考文献
Neidig et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 4617
反应条件
T=28°C; Product distribution;
参考文献
Kaufman; Levine
Chemistry and Industry (London, United Kingdom), 1959 , p. 1451
