2-甲氧基-5-羟基苯甲酸合成路线 （共 9 条）
反应条件
hydrogenchloride; sodium hydroxide in methanol
参考文献
Maynard, George D.; Le, Tieu-Binh
Patent: US2001/34343 A1, 2001 ;
反应条件
tert.-butyl lithium in pentane
Ambient temperature;
参考文献
Posner, Gary H.; Canella, Karen A.
Journal of the American Chemical Society, 1985 , vol. 107, # 8 p. 2571 - 2573
反应条件
sulfuric acid; water
T=55°C; 48 h;
参考文献
AMGEN INC.
Patent: WO2005/113494 A2, 2005 ;
Location in patent: Page/Page column 120 ;
WO 2005/113494 A2
反应条件
potassium hydroxide in ethanol; water
4 h; Heating;
参考文献
Hattori, Tetsutaro; Shimazumi, Yuhi; Goto, Hitoshi; Yamabe, Osamu; Morohashi, Naoya; Kawai, Wataru; Miyano, Sotaro
Journal of Organic Chemistry, 2003 , vol. 68, # 6 p. 2099 - 2108
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Schmidt, Ulrich; Boekens, Hilmar; Lieberknecht, Albrecht; Griesser, Helmut
Tetrahedron Letters, 1981 , vol. 22, # 49 p. 4949 - 4952
反应条件
1: NaOH / H2O
2: H2 / Pd/C-5percent / ethanol
View Scheme
参考文献
Schmidt, Ulrich; Boekens, Hilmar; Lieberknecht, Albrecht; Griesser, Helmut
Tetrahedron Letters, 1981 , vol. 22, # 49 p. 4949 - 4952
反应条件
1.1: K2CO3 / acetone / 19 h / Heating
1.2: 80 percent / acetone / 20 h / Heating
2.1: 82 percent / KOH / ethanol; H2O / 4 h / Heating
View Scheme
参考文献
Hattori, Tetsutaro; Shimazumi, Yuhi; Goto, Hitoshi; Yamabe, Osamu; Morohashi, Naoya; Kawai, Wataru; Miyano, Sotaro
Journal of Organic Chemistry, 2003 , vol. 68, # 6 p. 2099 - 2108
反应条件
Nitrous oxide in water
pH=8.5; γ-Irradiation; Product distributionG-values; Further Variations:dose;
参考文献
Gaisberger; Solar
Canadian Journal of Chemistry, 2001 , vol. 79, # 4 p. 394 - 404
反应条件
1: B2H6 / tetrahydrofuran
View Scheme
参考文献
Schmidt, Ulrich; Boekens, Hilmar; Lieberknecht, Albrecht; Griesser, Helmut
Tetrahedron Letters, 1981 , vol. 22, # 49 p. 4949 - 4952
