1-环己基-2-苯基-1-乙酮合成路线 （共 31 条）
反应条件
1: 1.) magnesium / 1.) ether; 2.) ether, r.t., 2 h
2: ethyl acetate
3: 10 percent potassium carbonate / benzene
View Scheme
参考文献
Ohta, Shunsaku; Hayakawa, Satoshi; Nishimura, Kazuko; Okamoto, Masao
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 3 p. 1058 - 1069
反应条件
1: ethyl acetate
2: 10 percent potassium carbonate / benzene
View Scheme
参考文献
Ohta, Shunsaku; Hayakawa, Satoshi; Nishimura, Kazuko; Okamoto, Masao
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 3 p. 1058 - 1069
参考文献
Rubin, Mordecai B.; Gutman, Arie L.
Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2511 - 2515
反应条件
hydrogenchloride
1.) THF, rt, 15 h, 2.) THF, EtOH, rt, 30 min; Yield given. Multistep reaction;
参考文献
Dinh, Tam Q.; Armstrong, Robert W.
Tetrahedron Letters, 1996 , vol. 37, # 8 p. 1161 - 1164
反应条件
1: chloroform
2: H2SO4 / -15 °C
View Scheme
参考文献
Bol'schuchin; Orlowa
Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 651,654; engl. Ausg. S. 719, 721
反应条件
1: diethyl ether
2: acetic acid; K2cr2O7; aqueous H2SO4
View Scheme
参考文献
Wenus-Danilowa; Bolschuchin
Zhurnal Obshchei Khimii, 1939 , vol. 9, p. 975,982
Chem. Zentralbl., 1940 , vol. 111, # I p. 1190
反应条件
1: diethyl ether
2: acetic acid; K2cr2O7; aqueous H2SO4
View Scheme
参考文献
Bergs
Chemische Berichte, 1934 , vol. 67, p. 1617,1619
反应条件
sodium hydroxide; dihydrogen peroxide; Et3CoLi
Yield given. Multistep reaction;
参考文献
Bestmann, Hans Juergen; Roeder, Thomas
Angewandte Chemie, 1983 , vol. 95, # 10 p. 812 - 813
反应条件
(i) LDA, hexane, THF, (ii) /BRN= 742163/; Multistep reaction;
参考文献
Krapcho,A.P. et al.
Journal of Organic Chemistry, 1977 , vol. 42, p. 1189 - 1194
反应条件
(i) NH2OH*HCl, (ii) H2, H+, Pd-C, EtOH; Multistep reaction;
参考文献
Ghosh; Bolt; Mrongovius
Arzneimittel-Forschung/Drug Research, 1978 , vol. 28, # 9 p. 1561 - 1564
