3-(3-吡啶基)-2-丙炔-1-醇合成路线 （共 8 条）
反应条件
quinoline; hydrogen; Lindlar's catalyst in methanol P=760 Torr; 18 h;
参考文献
Cheng, Yun-Xing; Dukat, Malgorzata; Dowd, Matthew; Fiedler, Wolfgang; Martin, Billy; Damaj, Mohamed Imad; Glennon, Richard A.
European Journal of Medicinal Chemistry, 1999 , vol. 34, # 2 p. 177 - 190
反应条件
copper(l) iodide; potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)); Tedicyp in N,N-dimethyl-formamide
T=100°C; 20 h;
参考文献
Feuerstein, Marie; Doucet, Henri; Santelli, Maurice
Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1717 - 1720
反应条件
N-ethyl-N,N-diisopropylamine; Pd(CH3CN)2Cl2 in tetrahydrofuran
参考文献
Grant III, Eugene B.; Henninger, Todd C.; Macielag, Mark J.; Guiadeen, Deodialsingh
Patent: US2003/125267 A1, 2003 ;
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine
Sonogashira coupling;
参考文献
Wessig, Pablo; Pick, Charlotte
Journal of Photochemistry and Photobiology A: Chemistry, 2011 , vol. 222, # 1 p. 263 - 265
反应条件
copper(l) iodide; potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)); Tedicyp in N,N-dimethyl-formamide
T=100°C; 20 h;
参考文献
Feuerstein, Marie; Doucet, Henri; Santelli, Maurice
Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1717 - 1720
反应条件
bis(triphenylphosphine)palladium(II)-chloride in triethylamine
参考文献
MIYAKE, HIROSHI; TAKE, KAZUHIKO; SHIGENAGA, SHINJI; AZAMI, HIDENORI; SASAKI, HIROSHI; EIKYU, YOSHITERU; NAKAI, KAZUO; ISHIDA, JUNYA; MANABE, TAKASHI; KONISHI, NOBUKIYO; TERASAKA, TADASHI
Patent: US2003/114668 A1, 2003 ;
反应条件
hydrogenchloride; potassium carbonate in aqueous dimethoxyethane
参考文献
Nikken Chemicals Co., Ltd.
Patent: US6306853 B1, 2001 ;
反应条件
[palladium(II)(bis(triphenylphosphanyl))dichloride]
Sonogashira coupling; Inert atmosphere;
参考文献
Garcia, Lidia; Pla-Quintana, Anna; Roglans, Anna; Parella, Teodor
European Journal of Organic Chemistry, 2010 , # 18 p. 3407 - 3415
