(S)-(-)-1-苯基-1-丙醇合成路线 （共 162 条）
反应条件
titanium(IV) isopropylate in diethyl ether; dichloromethane T=0°C; 1 h; Title compound not separated from byproducts.;
参考文献
Angewandte Chemie - International Edition, , vol. 47, # 6 p. 1088 - 1090
反应条件
SPB; water in tetrahydrofuran T=22°C;
参考文献
Angewandte Chemie, International Edition, , vol. 48, # 33 p. 6062 - 6064
Angewandte Chemie, , vol. 121, # 33 p. 6178 - 6180
反应条件
Birman's catalyst; nicotinic anhydride in dichloromethane T=0°C; 12 h; Resolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Heterocycles, , vol. 80, # 1 p. 169 - 175
反应条件
1: With (Sa)-2'-[(R)-hydroxy(phenyl)methyl]-(1,1'-binaphthalen)-2-ol; titanium (IV) isopropoxide in toluene T=-40°C; 1 h; Inert atmosphere; 2: With hydrogenchloride in water Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
European Journal of Organic Chemistry, , # 20 p. 3732 - 3736
反应条件
(1S)-(+)-3-exo-(dimethylamino)isoborneol in diethyl ether; toluene T=0°C; 6 h;
参考文献
Journal of Organometallic Chemistry, , vol. 382, # 1-2 p. 19 - 37
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate 15 h; Ambient temperature;
参考文献
Journal of the American Chemical Society, , vol. 111, # 23 p. 8737 - 8738
反应条件
50 U aminoacylase E.C. 3.5.1.14 in hexane Acetylation; 168 h;
参考文献
Tetrahedron Asymmetry, , vol. 11, # 8 p. 1801 - 1808
反应条件
Birman's catalyst; nicotinic anhydride in dichloromethane T=0°C; 12 h; Resolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Heterocycles, , vol. 80, # 1 p. 169 - 175
反应条件
1: With 4-bromooctafluorobutanetriethoxysilane; H2O*Rh(2+)*2C2H3O2(1-)*C18H24N2O2 in toluene T=30°C; 3 h; 2: With potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol T=0°C; 12 h; enantioselective reaction;
参考文献
Synlett, , vol. 23, # 20 p. 2957 - 2960
反应条件
1: With trimethylsilyl trifluoromethanesulfonate; benzo[1,3,2]dioxaborole; [Rh(acac)(COD)]2; (R)-1-(2-phenylquinazolin-4-yl)-2-(Ph2P)-naphthalene in tetrahydrofuran T=25°C; Addition; Hydroboration; 2 h; 2: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran T=20°C; Oxidation; Hydrolysis; 1 h; Further stages. Title compound not separated from byproducts.;
参考文献
Chemical Communications, , # 14 p. 1333 - 1334
