(S)-(-)-1-苯基-1-丙醇合成路线 （共 162 条）
反应条件
novozyme 435 in toluene T=60°C; 4 h; microwave irradiation;
参考文献
Tetrahedron Asymmetry, , vol. 18, # 13 p. 1618 - 1624
反应条件
benzoic acid anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Title compound not separated from byproducts.;
参考文献
Tetrahedron Letters, , vol. 48, # 47 p. 8314 - 8317
反应条件
in toluene toluene-soln. of Zn-complex added Bu2Zn; mixt. stirred at -78°C; added benzaldehyde; mixt. stirred at 0°C for 6 h; quenched (water); analyzed by HPLC;
参考文献
Journal of the American Chemical Society, , vol. 111, # 11 p. 4028 - 4036
反应条件
toluene-4-sulfonic acid in methanol 3 h;
参考文献
Chemische Berichte, , vol. 115, # 4 p. 1591 - 1606
反应条件
potassium carbonate in methanol Ambient temperature;
参考文献
Journal of the Chemical Society, Chemical Communications, , p. 598 - 600
反应条件
1: With (S)-2-methyl-quinazolinap rhodium; benzo[1,3,2]dioxaborole in tetrahydrofuran T=0°C; 2 h; 2: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran; ethanol T=0 - 20°C; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 69, # 20 p. 6572 - 6589
反应条件
1,3-bis-[(R)-1-(1-naphthyl)ethyl]-4,5-dihydro-3H-imidazolium tetrafluoroborate; potassium tert-butylate in tetrahydrofuran T=-78 - -20°C; 6.5 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Organic Letters, , vol. 7, # 7 p. 1347 - 1349
反应条件
Birman's catalyst; nicotinic anhydride in dichloromethane T=0°C; 12 h; Inert atmosphereResolution of racemate; TemperatureReagent/catalyst; enantioselective reaction;
参考文献
Helvetica Chimica Acta, , vol. 95, # 10 p. 1891 - 1911,21
Helvetica Chimica Acta, , vol. 95, # 10 p. 1891 - 1911
反应条件
chiral catalyst 2.) diethyl ether, -120 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 103, # 15 p. 4585 - 4586
反应条件
in benzene T=21°C; 20 h; lipase Amano P/Celite 577; Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 53, # 23 p. 5531 - 5534
