1-羟基环己烷-1-羧酸甲酯合成路线 （共 14 条）
反应条件
1: PCl5 / anschliessend Erwaermen mit methanol. NaOH 2: platinum; acetic acid; diethyl ether / Hydrogenation View Scheme
参考文献
Nippon Nogei Kagaku Kaishi, , vol. 25, p. 63,65
Chem.Abstr., , p. 9302
反应条件
phosphorus pentachloride anschliessend Erwaermen mit methanol. NaOH;
参考文献
Mitsui; Inagaki
Nippon Nogei Kagaku Kaishi, 1951 , vol. 25, p. 63,65
Chem.Abstr., 1953 , p. 9302
反应条件
phosphorus pentachloride; benzene anschliessendes Behandeln mit wss. K2CO3;
参考文献
Overberger; Kabasakalian
Journal of Organic Chemistry, 1956 , vol. 21, p. 1124,1126
反应条件
1: With pyridine; methyltrioxorhenium (VII) in acetic acid; acetonitrile
T=0 - 20°C; Oxidation;
2: With potassium fluoride in methanol
Substitution; 1 h; Further stages.;
参考文献
Stankovic, Sasa; Espenson, James H.
Journal of Organic Chemistry, 2000 , vol. 65, # 18 p. 5528 - 5530
参考文献
Tarbouriech
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1909 , vol. 149, p. 605
反应条件
Amberlyst 15
T=60°C; 48 h;
参考文献
Greenlee, William J.; Thorsett, Eugene D.
Journal of Organic Chemistry, 1981 , vol. 46, p. 5351 - 5353
反应条件
in methanol
T=0 - 20°C; 5 h; Inert atmosphere;
参考文献
Maegawa, Tomohiro; Otake, Kazuki; Hirosawa, Keiichi; Goto, Akihiro; Fujioka, Hiromichi
Organic Letters, 2012 , vol. 14, # 18 p. 4798 - 4801
反应条件
1: aq. hydrochloric acid
2: sulfuric acid
View Scheme
参考文献
Suzuki, Itsuko; Tanaka, Ryoko; Yamaguchi, Akinori; Maki, Shin-Ichiro; Misawa, Hiroaki; Tokumaru, Katsumi; Nakagaki, Ryoichi; Sakuragi, Hirochika
Bulletin of the Chemical Society of Japan, 1999 , vol. 72, # 1 p. 103 - 113
反应条件
2: fuming hydrochloric acid
3: concentrated sulfuric acid
View Scheme
参考文献
Tarbouriech
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1909 , vol. 149, p. 605
反应条件
1: water; hydrogenchloride / 2 h / 20 - 60 °C / |Inert atmosphere
2: methanol / 5 h / 0 - 20 °C / |Inert atmosphere
View Scheme
参考文献
Maegawa, Tomohiro; Otake, Kazuki; Hirosawa, Keiichi; Goto, Akihiro; Fujioka, Hiromichi
Organic Letters, 2012 , vol. 14, # 18 p. 4798 - 4801
