1,3-二氨基-2-羟基丙烷合成路线 （共 34 条）
参考文献
Shin-Etsu Chemical Co., Ltd.
Patent: EP2412733 A1, 2012 ;
反应条件
in methanol T=60°C; 24 h; Yields of byproduct given;
参考文献
Leung, Man-Kit; Lai, Jun-Liang; Lau, King-Hang; Yu, Hsiao-Hua; Hsiao, Hsiang-Ju
Journal of Organic Chemistry, 1996 , vol. 61, # 12 p. 4175 - 4179
反应条件
methanol; sulfur T=120°C; P=5148.6 Torr;
参考文献
Monsanto Chem.Co.
Patent: US2874149 , 1957 ;
参考文献
Hafner; Evans
Journal of Organic Chemistry, 1959 , vol. 24, p. 1157
反应条件
triethylamine in dichloromethane T=0°C; 1 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 75, p. 308 - 326
反应条件
sodium hydroxide; acetic acid 2.) RT, 5 min; Yield given. Multistep reaction;
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 38, # 10 p. 897 - 905
参考文献
Novo Nordisk Health Care AG
Patent: US2011/306548 A1, 2011 ;
反应条件
sodium hydroxide; trimethylhexadecylammonium chloride in water 24 h; Ambient temperature;
参考文献
Sato; Mori; Iida
Synthesis, 1992 , # 6 p. 539 - 540
参考文献
Johnston; McCaleb; Opliger; Laster; Montgomery
Journal of medicinal chemistry, 1971 , vol. 14, # 17 p. 600 - 614
反应条件
4-(N,N-dimethlyamino)pyridine in methanol 5.5 h; Heating;
参考文献
Korshun, Vladimir A.; Pestov, Nikolai B.; Nozhevnikova, Elena V.; Prokhorenko, Igor A.; Gontarev, Sergei V.; Berlin, Yuri A.
Synthetic Communications, 1996 , vol. 26, # 13 p. 2531 - 2547
