4-羟基-3-硝基苯甲酸合成路线 （共 85 条）
反应条件
water; sodium hydroxide T=100°C;
参考文献
CENTAURUS BIOPHARMA CO., LTD.; XIAO, Dengming; ZHU, Li; HU, Yuandong; YU, Rong; HU, Wei; ZHAO, Na; PENG, Yong; LUO, Hong; HAN, Yongxin
Patent: WO2013/97773 A1, 2013 ;
Location in patent: Paragraph 0266 ;
反应条件
Mg(NO3)2*6H2O; AMA T=20°C; 1.5 h; Neat (no solvent); regioselective reaction;
参考文献
Hosseini-Sarvari, Mona; Tavakolian, Mina
Journal of Chemical Research, 2008 , # 12 p. 722 - 724
反应条件
ammonium cerium(IV) nitrate in acetonitrile T=60 - 70°C; 0.25 h;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 22, # 11 p. 1129 - 1131
反应条件
ammonium cerium(IV) nitrate in acetonitrile T=20°C; 0.333333 h;
参考文献
Journal of the Chinese Chemical Society, , vol. 52, # 3 p. 581 - 588
反应条件
phosphate buffer; alpha-cyclodextrin T=25°C; also in the presence of β-cyclodextrin, var. conc. of α- and β-cyclodextrin; Rate constant;
参考文献
Journal of the American Chemical Society, , vol. 114, # 2 p. 620 - 627
反应条件
alkaline permanganate T=90 - 100°C;
参考文献
Journal of the American Chemical Society, , vol. 42, p. 2300
反应条件
1: concentrated hydrochloric acid 2: alkaline permanganate / 90 - 100 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 42, p. 2300
参考文献
Journal of the American Chemical Society, , vol. 47, p. 1161
Journal of the American Chemical Society, , vol. 48, p. 465
反应条件
1: sulfuric acid; nitric acid / -5 - 0 °C 2: NaOH-solution View Scheme
参考文献
Journal of the American Chemical Society, , vol. 47, p. 1161
Journal of the American Chemical Society, , vol. 48, p. 465
反应条件
phosphate buffer; β-cyclodextrin; sodium chloride in acetonitrile T=25°C; pH 7.65; also with ether CD or PEI alone; Rate constant;
参考文献
Journal of the American Chemical Society, , vol. 114, # 20 p. 7916 - 7917
