(S)-(+)-2-辛醇合成路线 （共 200 条）
反应条件
potassium tert-butylate in tetrahydrofuran Ambient temperature; Yield given;
参考文献
Tetrahedron Letters, , vol. 27, # 26 p. 2945 - 2948
反应条件
potassium carbonate in methanol 1 h; Ambient temperature; Yield given;
参考文献
Tetrahedron Asymmetry, , vol. 10, # 10 p. 1913 - 1926
反应条件
1: 1.) Br2 / 1.) CCl4, RT, 6 h, irradiation, 2.) MeOH, RT, 24 h 2: baker's yeast, sucrose / H2O / 144 h / 37 °C 3: pyridine / 2 h / Ambient temperature 4: n-Bu3SnH, 2,2'-azobis(2-methylpropionitrile) / toluene / 110 °C 5: aq. K2CO3 / methanol / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 10, # 10 p. 1913 - 1926
反应条件
1: baker's yeast, sucrose / H2O / 144 h / 37 °C 2: pyridine / 2 h / Ambient temperature 3: n-Bu3SnH, 2,2'-azobis(2-methylpropionitrile) / toluene / 110 °C 4: aq. K2CO3 / methanol / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 10, # 10 p. 1913 - 1926
反应条件
1: pyridine / 2 h / Ambient temperature 2: n-Bu3SnH, 2,2'-azobis(2-methylpropionitrile) / toluene / 110 °C 3: aq. K2CO3 / methanol / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 10, # 10 p. 1913 - 1926
反应条件
1: n-Bu3SnH, 2,2'-azobis(2-methylpropionitrile) / toluene / 110 °C 2: aq. K2CO3 / methanol / 1 h / Ambient temperature View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 10, # 10 p. 1913 - 1926
反应条件
1: 35 percent / dimethylformamide; hexamethylphosphoric acid triamide / 1 h / 55 °C 2: 100 percent / LiAlH4 / tetrahydrofuran 3: 56 percent / pyridine 4: 93 percent / LiAlH4 / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 199 - 202
反应条件
1: 56 percent / pyridine 2: 93 percent / LiAlH4 / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 199 - 202
反应条件
1: 1.) oxalyl chloride/DMSO; 2.) Et3N / CH2Cl2 / 1.) -78 deg C, 17 min; 2.) a.) -78 deg C, 5 min; b.) RT, 30 min 2: K2CO3 / methanol / 12 h / Ambient temperature View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 285, p. 83 - 94
反应条件
1: paratoluene sulfonic acid / cyclohexane / 10 h / Heating 2: 96 percent / BF3 / diethyl ether / 0.25 h / -55 °C 3: PCC 4: Na / diethyl ether / 96 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 45, # 2 p. 507 - 516
