4,4’-二甲基二苯硫醚合成路线 （共 108 条）
参考文献
Gilman; Smith; Parker
Journal of the American Chemical Society, 1925 , vol. 47, p. 858
反应条件
sodium tetrahydroborate
T=260 - 280°C; 2 h;
参考文献
Nose, Atsuko; Kudo, Tadahiro
Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 5 p. 1770 - 1776
反应条件
1: 29 percent Chromat. / FSO3H*SbF5 (1:1) / 1,1,2-trichloro-1,2,2-trifluoro-ethane; liquid sulphur dioxide / 1.) -30 deg C 2.) 0 deg C, 1.5 h
2: 90 percent Chromat. / HF*SbF5 (1:1) / liquid sulphur dioxide / -5 °C
View Scheme
参考文献
Laali, Kenneth Khosrow; Nagvekar, Devdatt S.
Journal of Organic Chemistry, 1991 , vol. 56, # 5 p. 1867 - 1874
反应条件
1: 77 percent Chromat. / FSO3H*SbF5 (1:1) / 1,1,2-trichloro-1,2,2-trifluoro-ethane
2: 90 percent Chromat. / HF*SbF5 (1:1) / liquid sulphur dioxide / -5 °C
View Scheme
参考文献
Laali, Kenneth Khosrow; Nagvekar, Devdatt S.
Journal of Organic Chemistry, 1991 , vol. 56, # 5 p. 1867 - 1874
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; caesium carbonate; palladium dichloride in N,N-dimethyl-formamide
T=185°C; 20 h; Inert atmosphere;
参考文献
Ortgies, Dirk H.; Barthelme, Alexandre; Aly, Sara; Desharnais, Brigitte; Rioux, Steven; Forgione, Pat
Synthesis (Germany), 2013 , vol. 45, # 5 art. no. SS-2012-M0902-OP, p. 694 - 702
反应条件
CuF2; sulfur in dimethyl sulfoxide
T=100°C; Chan-Lam Coupling; 12 h; Reagent/catalyst; Overall yield = 73 percent;
参考文献
Yu, Jin-Tao; Guo, Huan; Yi, Yuanqiuqiang; Fei, Haiyang; Jiang, Yan
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 4 p. 749 - 752
反应条件
silver carbonate in dimethyl sulfoxide; N,N-dimethyl-formamide
T=120°C; 0.166667 h; Microwave irradiation;
参考文献
Li, Junchen; Bi, Xiaojing; Wang, Hongmei; Xiao, Junhua
RSC Advances, 2014 , vol. 4, # 37 p. 19214 - 19217
反应条件
KC8 in tetrahydrofuran
1 h; Ambient temperatureorder of cleavage, cleavage ratio; Product distribution;
参考文献
Beak, Peter; Sullivan, Thomas A.
Journal of the American Chemical Society, 1982 , vol. 104, # 16 p. 4450 - 4457
反应条件
SbF5; epoxysulfonyl fluoride in 1,2,2-trifluoro-trichloroethane
参考文献
Laali, Kenneth Khosrow; Nagvekar, Devdatt S.
Journal of Organic Chemistry, 1991 , vol. 56, # 5 p. 1867 - 1874
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; caesium carbonate; palladium dichloride in N,N-dimethyl-formamide
T=185°C; 20 h; Inert atmosphere;
参考文献
Ortgies, Dirk H.; Barthelme, Alexandre; Aly, Sara; Desharnais, Brigitte; Rioux, Steven; Forgione, Pat
Synthesis (Germany), 2013 , vol. 45, # 5 art. no. SS-2012-M0902-OP, p. 694 - 702
