3-羟基-4-甲氧基苯甲醛合成路线 （共 405 条）
反应条件
1: toluene / 4 h / 80 °C 2: sodium hydroxide / methanol / 4 h / 70 °C View Scheme
参考文献
Li, Xiao-Dong; Kang, Shuai-Tao; Li, Guo-Yu; Li, Xian; Wang, Jin-Hui
Molecules, 2011 , vol. 16, # 5 p. 3580 - 3596
参考文献
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 104, p. 134
反应条件
1: K2CO3 / dimethylformamide 2: NH4OAc; AcOH 3: LAH / tetrahydrofuran 4: H2 / Pd/C View Scheme
参考文献
Xi, Bao-Min; Jiang, Zhen-Zhou; Zou, Jian-Wei; Ni, Pei-Zhou; Chen, Wen-Hua
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 2 p. 783 - 788
反应条件
1: Ag2O 2: concentrated H2SO4 View Scheme
参考文献
Pearl; Beyer
Journal of the American Chemical Society, 1953 , vol. 75, p. 2627,2628
反应条件
1: 91 percent / K2CO3 / dimethylformamide / 12 h / 60 °C 2: 79 percent / NH4OAc / 3 h / Heating 3: LiAlH4 / tetrahydrofuran / 1.5 h / Heating 4: Na2CO3 / ethanol / 12 h / 150 °C View Scheme
参考文献
Anada, Masahiro; Mita, Orie; Watanabe, Hiroko; Kitagaki, Shinji; Hashimoto, Shunichi
Synlett, 1999 , # 11 p. 1775 - 1777
反应条件
caesium carbonate in N,N-dimethyl-formamide T=20°C; 20 h;
参考文献
CHIESI FARMACEUTICI S.p.A.
Patent: EP2070913 A1, 2009 ;
Location in patent: Page/Page column 17 ;
EP 2070913 A1
参考文献
Deshpande, V. H.; Gokhale, Neelam J.
Tetrahedron Letters, 1992 , vol. 33, # 29 p. 4213 - 4216
参考文献
SmithKline Beecham Corporation
Patent: US5393788 A1, 1995 ;
US 5393788 A
反应条件
1: hydrogen 2: sodium hydroxide / ethanol View Scheme
参考文献
Arnarp; Bielawski; Dahlin; Dahlman; Enzell; Pettersson
Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1989 , vol. 43, # 1 p. 44 - 50
反应条件
potassium carbonate in acetonitrile 19 h; Heating;
参考文献
Goeschke, Richard; Stutz, Stefan; Heinzelmann, Walter; Maibaum, Juergen
Helvetica Chimica Acta, 2003 , vol. 86, # 8 p. 2848 - 2870
