3-羟基-4-甲氧基苯甲醛合成路线 （共 405 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide 48 h; Ambient temperature;
参考文献
Janin; Bisagni
Tetrahedron, 1993 , vol. 49, # 45 p. 10305 - 10316
反应条件
1: 92.5 percent / anhydr. potassium carbonate / dimethylformamide / 48 h / Ambient temperature 2: 73 percent / diethyl ether / 2 h / Ambient temperature 3: 88 percent / potassium chromate / acetone / 0.75 h / 10 °C View Scheme
参考文献
Janin; Bisagni
Tetrahedron, 1993 , vol. 49, # 45 p. 10305 - 10316
反应条件
piperidine in pyridine 1.) 105 deg C, 3 h, 2.) 145 deg C, 1 h;
参考文献
Pearson, Anthony J.; Lee, Kieseung
Journal of Organic Chemistry, 1994 , vol. 59, # 9 p. 2304 - 2313
反应条件
1: toluene / 4 h / 80 °C 2: sodium hydroxide / methanol / 4 h / 70 °C View Scheme
参考文献
Li, Xiao-Dong; Kang, Shuai-Tao; Li, Guo-Yu; Li, Xian; Wang, Jin-Hui
Molecules, 2011 , vol. 16, # 5 p. 3580 - 3596
参考文献
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1922 , vol. <2> 104, p. 134
反应条件
1: diethyl ether 2: hydrogen / Pd-C View Scheme
参考文献
Arnarp; Bielawski; Dahlin; Dahlman; Enzell; Pettersson
Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1989 , vol. 43, # 1 p. 44 - 50
反应条件
1.1: 88 percent / sodium formate; formic acid; hydroxylamine sulfate / 8 h / 85 °C 2.1: 95 percent / K2CO3 / dimethylformamide / 10 h / 85 °C 3.1: 95 percent / aq. H2SO4; HNO3; AcOH / 50 h / 20 °C 4.1: 75 percent / sodium dithionite / H2O / 20 - 50 °C 5.1: 38 percent / KOH / 2-methyl-butan-2-ol / 82 °C 6.1: formamide / 20 - 100 °C 6.2: 78 percent / 7 h / 100 °C 7.1: 90 percent / POCl3; triethylamine / toluene / 24 h / 58 °C 8.1: 91 percent / triethylamine / propan-2-ol / 288 h / Heating 9.1: 54 percent / LiCl / dimethylformamide / 15 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 15 p. 4102 - 4106
反应条件
1: 95 percent / DMAP, Et3N / tetrahydrofuran; diethyl ether / 14 h / Ambient temperature 2: 87.5 percent / m-chloroperbenzoic acid / CH2Cl2 / 2.5 h / Heating 3: Cs2CO3 / dimethylformamide / 5 h / Ambient temperature 4: 25percent aq. NH3 / dimethylformamide / 0.5 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 11 p. 2165 - 2170
参考文献
Journal of Agricultural and Food Chemistry, , vol. 51, # 3 p. 594 - 600
反应条件
1.1: 92 percent / triethylamine / dimethylformamide / 20 °C 2.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 2.2: tetrahydrofuran / 5 h / 20 °C 3.1: 90 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 20 °C 4.1: 92 percent / potassium carbonate / acetone / 5 h / Heating View Scheme
参考文献
Gao, Mingzhang; Wang, Min; Miller, Kathy D.; Sledge, George W.; Hutchins, Gary D.; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 22 p. 5767 - 5772
