1-噻吩-3-基-丙烷-2-酮合成路线 （共 7 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride in benzene
react. mixt. washed (aq. KF); extn.of org. layer (ether); dried over MgSO4; product isolated by distn. (reduced pressure); acetonylated by chromy. (silica gel);
参考文献
Kosugi; Miyajima; Nakanishi; Sano; Migita
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 10 p. 3383 - 3385
反应条件
bis-triphenylphosphine-palladium(II) chloride in benzene
react. mixt. washed (aq. KF); extn.of org. layer (ether); dried over MgSO4; product isolated by distn. (reduced pressure); acetonylated by chromy. (silica gel);
参考文献
Kosugi; Miyajima; Nakanishi; Sano; Migita
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 10 p. 3383 - 3385
反应条件
in tetrahydrofuran
T=0 - 20°C; Inert atmosphere;
参考文献
Kaschel, Johannes; Schneider, Tobias F.; Schirmer, Patrick; Maass, Christian; Stalke, Dietmar; Werz, Daniel B.
European Journal of Organic Chemistry, 2013 , # 21 p. 4539 - 4551
反应条件
NiBr2bipy in N,N-dimethyl-formamide
Ambient temperatureelectrolysis; nickel-sponge cathode, aluminium rod anode, NBu4BF4 supporting electrolyte; current intensity 0.15 to 0.2 A;
参考文献
Durandetti, Muriel; Perichon, Jacques; Nedelec, Jean-Yves
Tetrahedron Letters, 1997 , vol. 38, # 50 p. 8683 - 8686
反应条件
hydrogenchloride; iron(III) chloride; iron
参考文献
Campaigne; McCarthy
Journal of the American Chemical Society, 1954 , vol. 76, p. 4466
反应条件
1: ethanol; butylamine
2: aqueous hydrochloric acid; iron-turnings; iron (III)-chloride
View Scheme
参考文献
Campaigne; McCarthy
Journal of the American Chemical Society, 1954 , vol. 76, p. 4466
反应条件
[Pd(η3-1-Ph-allyl)(μ-Cl)]2; (Mor-DalPhos); caesium carbonate
T=90°C; 16 h; Inert atmospheresealed vial;
参考文献
Hesp, Kevin D.; Lundgren, Rylan J.; Stradiotto, Mark
Journal of the American Chemical Society, 2011 , vol. 133, # 14 p. 5194 - 5197
