17β-羟基雌甾-4,9-二烯-3-酮合成路线 （共 9 条）
反应条件
sodium borohydride; acetic acid in tetrahydrofuran; methanol
参考文献
US5620966 A1, ;
US 5620966 A
1089-78-7(8R,9S,13S,14S,17S)-17-羟基-13-甲基-2,4,6,7,8,9,11,12,14,15,16,17-十二氢-1H-环戊并[a]菲-3-酮
→
反应条件
polyvinyl pyridine; polyvinylpyridiniumbromide-perbromide in chloroform 20 h; Ambient temperature;
参考文献
Menzenbach; Hubner
Zeitschrift fur Chemie, 1986 , vol. 26, # 10 p. 371 - 371
反应条件
1.1: aq. oxalic acid / acetone / 3 h / 23 °C 2.1: polyvinyl pyridinium bromide perbromide; polyvinyl pyridine; pyridine / 24 h / 23 °C 2.2: 3.32 g / aq. HCl / pH 2 - 3 View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 21 p. 4985 - 4988
反应条件
1: 98 percent / NaBH4 / methanol / 0.25 h / Ambient temperature 2: 23 mg / 70percent HClO4 / acetic acid / 0.17 h / ice-bath to room temperature View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 13 p. 1529 - 1536
反应条件
perchloric acid in acetic acid 0.166667 h; ice-bath to room temperature;
参考文献
Ranjith, H.; Dharmaratne, W.; Kilgore, James L.; Roitman, Esther; Shackleton, Cedric; Caspi, Eliahu
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 13 p. 1529 - 1536
反应条件
perchloric acid 0.166667 h; ice-bath to room temperature; Title compound not separated from byproducts;
参考文献
Ranjith, H.; Dharmaratne, W.; Kilgore, James L.; Roitman, Esther; Shackleton, Cedric; Caspi, Eliahu
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 13 p. 1529 - 1536
反应条件
1: 92 percent / H2SO4 / benzene; CH2Cl2 / 2.5 h / Heating 2: 99.3 percent / N-methylmorpholine N-oxide, (nC3H7)4NRuO4 / CH2Cl2 / 0.25 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 11 p. 2113 - 2129
反应条件
tetrapropylammonium perruthennate 3 h;
参考文献
Napolitano, Elio; Fiaschi, Rita; Hanson, Robert N.
Gazzetta Chimica Italiana, 1990 , vol. 120, # 5 p. 323 - 326
反应条件
1: O2, methylene blue / acetone; benzene / Ambient temperature; Irradiation 2: (i) NaBH4, (ii) TsOH View Scheme
参考文献
Maumy,M.; Rigaudy,J.
Bulletin de la Societe Chimique de France, 1975 , p. 1879 - 1882
