(3-氯苯)(吡啶-3-基)甲酮合成路线 （共 4 条）
反应条件
caesium carbonate; 1,3-bis(2,4,6-trimethylphenyl)imidazolinium chloride; palladium diacetate in 1,4-dioxane
T=120°C; P=37503 Torr; 30 h;
参考文献
Maerten, Eddy; Sauthier, Mathieu; Mortreux, Andre; Castanet, Yves
Tetrahedron, 2007 , vol. 63, # 3 p. 682 - 689
反应条件
manganese(IV) oxide in dichloromethane
264 h;
参考文献
Deane, Karen J.; Summers, Robert L.; Lehane, Adele M.; Martin, Rowena E.; Barrow, Russell A.
ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 5 p. 576 - 581
反应条件
1.1: n-butyllithium / cyclohexane; diethyl ether / 1 h / -78 °C
1.2: 2 h / 20 °C
2.1: manganese(IV) oxide / dichloromethane / 264 h
View Scheme
参考文献
Deane, Karen J.; Summers, Robert L.; Lehane, Adele M.; Martin, Rowena E.; Barrow, Russell A.
ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 5 p. 576 - 581
反应条件
1.1: n-butyllithium / cyclohexane; diethyl ether / 1 h / -78 °C
1.2: 2 h / 20 °C
2.1: manganese(IV) oxide / dichloromethane / 264 h
View Scheme
参考文献
Deane, Karen J.; Summers, Robert L.; Lehane, Adele M.; Martin, Rowena E.; Barrow, Russell A.
ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 5 p. 576 - 581
