反应条件
1: 75 percent / NaBH4 / CHCl3; propan-2-ol 2: PCl3, Et3N / 0.33 h / 0 °C 3: Et3N / 0 deg C, 75 min then r.t., 30 min 4: tert-butyl hydroperoxide / decane / 1.5 h / -20 °C 5: 90 percent / NaOMe / methanol 6: 0.05 M phosphate buffer, carboxylate esterase, β-glucuronidase / 37 °C / pH=7.4 View Scheme
参考文献
Tetrahedron Letters, , vol. 38, # 51 p. 8795 - 8798