4-(2-呋喃基)-3-丁烯-2-酮合成路线 （共 89 条）
参考文献
Polivin, Yu. N.; Karakhanov, R. A.; Kelarev, V. I.; Ugrak, B. I.; Panina, M. E.
Russian Chemical Bulletin, 1993 , vol. 42, # 5 p. 878 - 880
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 5 p. 921 - 923
参考文献
Arsenjuk
Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 766,767, 768; engl. Ausg. S. 877, 878, 879
反应条件
1: concentrated hydrochloric acid; ethanol
2: diluted sodium methylate / Electrolysis.an Platinelektroden
View Scheme
参考文献
Hunsdiecker
Chemische Berichte, 1942 , vol. 75, p. 467
Chemische Berichte, 1947 , vol. 80, p. 142
反应条件
sodium alkoxide
T=95°C; 4 h;
参考文献
Pevzner, L. M.; Ignat'ev, V. M.; Ionin, B. I.
J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 1 p. 69 - 71,59 - 61
反应条件
PHT in tetrahydrofuran
T=20°C; 24 h;
参考文献
Babu, K. Suresh; Li, Xing-Cong; Jacob, Melissa R.; Zhang, Qifeng; Khan, Shabana I.; Ferreira, Daneel; Clark, Alice M.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7877 - 7886
反应条件
1: 59 percent / pyrrolidone hydrotribromide / tetrahydrofuran / 24 h / 20 °C
2: 56 percent / tetrahydrofuran / Heating
3: 93 percent / aq. NaOH / methanol / 20 °C
View Scheme
参考文献
Babu, K. Suresh; Li, Xing-Cong; Jacob, Melissa R.; Zhang, Qifeng; Khan, Shabana I.; Ferreira, Daneel; Clark, Alice M.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 26 p. 7877 - 7886
反应条件
ethanol; nickel catalysts
T=150°C; P=73550.8 - 147102 Torr; Hydrogenation;
参考文献
Xu, Wenjie; Xia, Qineng; Zhang, Yu; Guo, Yong; Wang, Yanqin; Lu, Guanzhong
ChemSusChem, 2011 , vol. 4, # 12 p. 1758 - 1761
反应条件
ethanol; nickel
T=180°C; P=110326 - 147102 Torr; Hydrogenation;
参考文献
Alexander et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 5506,5507
Journal of the American Chemical Society, 1951 , vol. 73, p. 2725,2726
反应条件
hydrogen in ethanol
T=140°C; P=15001.5 Torr; Autoclave;
参考文献
Xu, Wenjie; Xia, Qineng; Zhang, Yu; Guo, Yong; Wang, Yanqin; Lu, Guanzhong
ChemSusChem, 2011 , vol. 4, # 12 p. 1758 - 1761
反应条件
hydrogen in tetrahydrofuran
T=130°C; P=7500.75 Torr; Autoclave;
参考文献
Xu, Wenjie; Xia, Qineng; Zhang, Yu; Guo, Yong; Wang, Yanqin; Lu, Guanzhong
ChemSusChem, 2011 , vol. 4, # 12 p. 1758 - 1761
