in tetrahydrofuran (N2); addn. of 1.1 equiv. of butyllithium in hexanes to THF soln. of bromoarene deriv. at -78°C, stirring for 60-120 min at -78°C,addn. of 1.1 equiv. of borate deriv., warming to room temp. overnight; addn. of 2 M aq. HCl, extn (CH2Cl2), recrystn.;
参考文献
Walther, Mathieu E.; Wenger, Oliver S.
Dalton Transactions, 2008 , # 44 p. 6311 - 6318
1: 13 percent / tetrakis(triphenylphosphine)palladium(0); potassium tert-butoxide / toluene / 4 h / 80 °C 2: 85 percent / trifluoroacetic acid / CH2Cl2 / 6 h View Scheme
参考文献
Nielsen, Simon Feldbk; Nielsen, Elsebet stergaard; Olsen, Gunnar M.; Liljefors, Tommy; Peters, Dan
Journal of Medicinal Chemistry, 2000 , vol. 43, # 11 p. 2217 - 2226
