1: water / 48 h / 40 °C 2: palladium on carbon; sulfuric acid; hydrogen / ethanol; water / 24 h / 50 °C / 836.06 Torr 3: hydrogenchloride; water / 30 h / Reflux View Scheme
1: palladium on carbon; hydrogen bromide; hydrogen / ethanol; water / 30 h / 40 °C / 836.06 Torr 2: hydrogenchloride; water / 30 h / Reflux View Scheme
(R)-lt;lt;N-n-Hexadecyl-N-(2-hydroxy-1-propyl)aminogt;methylgt;pyridine; Cu in various solvent(s) T=25°C; enantioselectivity of cleavage; other chiral ligands; Rate constant;
参考文献
Journal of Organic Chemistry, , vol. 59, # 15 p. 4194 - 4201