3-(4,5-二氢-1H-咪唑-2-基)吡啶合成路线 (共 10 条)
反应条件
trichloroisocyanuric acid in neat (no solvent) T=110°C; 2.5 h; chemoselective reaction;
参考文献
Hojati, Seyedeh Fatemeh; Nezhadhoseiny, Seyede Atefe
Journal of the Serbian Chemical Society, 2012 , vol. 77, # 9 p. 1181 - 1189,9
反应条件
iodine; potassium carbonate; potassium iodide in water T=90°C; 0.75 h;
参考文献
Gogoi, Pranjal; Konwar, Dilip
Tetrahedron Letters, 2006 , vol. 47, # 1 p. 79 - 82
反应条件
1: ethylenediamine With trimethylaluminum in toluene T=20°C; 1 h; 2: pyridine-3-carboxylic acid methyl ester in toluene Heating; Further stages.;
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 21 p. 4724 - 4731
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; caesium carbonate in toluene 16 h; Inert atmosphereReflux;
参考文献
Geden, Joanna V.; Pancholi, Alpa K.; Shipman, Michael
Journal of Organic Chemistry, 2013 , vol. 78, # 8 p. 4158 - 4164
反应条件
1: dichloromethane / 0.33 h / 0 °C 2: N-bromosuccinmide / dichloromethane / 16 h / 0 - 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 53, # 23 p. 2876 - 2880
反应条件
trimethylaluminum Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 46, # 13 p. 2824 - 2826
参考文献
Journal of the Chemical Society, , p. 497,500
参考文献
DE687196 , ;
DRP/DRBP Org.Chem.
反应条件
potassium permanganate; montmorillonite K-10 in acetonitrile T=20°C; 1.25 h;
参考文献
Mohammadpoor-Baltork, Iraj; Abdollahi-Alibeik, Mohammad
Canadian Journal of Chemistry, 2005 , vol. 83, # 2 p. 110 - 114