2,3,4,9-四氢-9-甲基-1H-咔唑合成路线 （共 38 条）
反应条件
TEMPO+BF4- in water; acetonitrile 1 h;
参考文献
Bobbitt, James M.; Guttermuth, M. Cecile Flores; Ma, Zhenkun; Tang, Huitong
Heterocycles, 1990 , vol. 30, # 2 p. 1131 - 1140
反应条件
palladium on activated charcoal; trimethylbenzene
参考文献
Horning et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 3935
反应条件
Zersetzen des Reaktionsprodukts mit Schwefelwasserstoff;
参考文献
Perkin; Plant
Journal of the Chemical Society, 1921 , vol. 119, p. 1836
Journal of the Chemical Society, 1923 , vol. 123, p. 676
参考文献
Perkin; Plant
Journal of the Chemical Society, 1923 , vol. 123, p. 694
反应条件
Electrolysis; 9-methyl-'cis'-1,2,3,4,10,11-hexahydro-carbazole;
参考文献
v. Braun; Ritter
Chemische Berichte, 1922 , vol. 55, p. 3795
Full Text Show Details
Perkin; Plant
Journal of the Chemical Society, 1924 , vol. 125, p. 1508
Journal of the Chemical Society, 1925 , vol. 127, p. 1141
反应条件
1: 1,2,3,4,10,11-hexahydrocarbazole With sodium hydride in tetrahydrofuran
T=20°C; 1 h;
2: methyl iodide in tetrahydrofuran
T=20°C; 0.25 h; Further stages.;
参考文献
Pitts; Harrison; Moody
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 9 p. 955 - 977
反应条件
hydrogenchloride; platinum (II) chloride in 1,4-dioxane
T=60°C;
参考文献
Liu, Cong; Han, Xiaoqing; Wang, Xiang; Widenhoefer, Ross A.
Journal of the American Chemical Society, 2004 , vol. 126, # 12 p. 3700 - 3701
反应条件
tris(triphenylphosphine)ruthenium(II) chloride in 1,4-dioxane
T=180°C; 50 h;
参考文献
Tsuji, Yasushi; Huh, Keun-Tae; Watanabe, Yoshihisa
Journal of Organic Chemistry, 1987 , vol. 52, # 9 p. 1673 - 1680
反应条件
palladium diacetate; caesium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in ethylene glycol dimethyl ether
T=90°C; 3 h; Inert atmosphere;
参考文献
Yagoubi, Myriam; Cruz, Ana C. F.; Nichols, Paula L.; Elliott, Richard L.; Willis, Michael C.
Angewandte Chemie - International Edition, 2010 , vol. 49, # 43 p. 7958 - 7962
反应条件
1: With copper(l) iodide; potassium carbonate; N,N-dimethylethylenediamine in toluene
T=110°C; Fischer Indole Synthesis; 24 h; Schlenk techniqueInert atmosphere;
2: With zinc(II) chloride in toluene
T=90°C; Fischer Indole Synthesis; 1 h;
参考文献
Zhan, Fuxu; Liang, Guangxin
Angewandte Chemie - International Edition, 2013 , vol. 52, # 4 p. 1266 - 1269
Angew. Chem., 2012 , vol. 125, # 4 p. 1304 - 1307,4
