2,3,4,9-四氢-9-甲基-1H-咔唑合成路线 （共 38 条）
反应条件
indole in o-xylene
96 h; Heating;
参考文献
Davies, David E.; Gilchrist, Thomas L.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 7 p. 1479 - 1481
反应条件
1.1: 1.5 h / 20 - 80 °C / |Inert atmosphere
2.1: sodium / ethanol / 20 h / 100 °C / |Sealed tube; |Darkness
3.1: copper(l) iodide; potassium carbonate; N,N-dimethylethylenediamine / toluene / 24 h / 110 °C / |Schlenk technique; |Inert atmosphere
3.2: 1 h / 90 °C
View Scheme
参考文献
Zhan, Fuxu; Liang, Guangxin
Angewandte Chemie - International Edition, 2013 , vol. 52, # 4 p. 1266 - 1269
Angew. Chem., 2012 , vol. 125, # 4 p. 1304 - 1307,4
反应条件
1: 24 percent / methanol / 35 h / Irradiation
2: 52 percent / quinoline, sodium carbonate / 2-methoxy-ethanol / 0.75 h / Heating
3: ethane-1,2-diol / Heating
View Scheme
参考文献
El-Hamamy, Ahmad A.; Hill, John; Townend, John
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 573 - 580
反应条件
1: 38 percent / benzene / 1 h / Irradiation
2: 52 percent / quinoline, sodium carbonate / 2-methoxy-ethanol / 0.75 h / Heating
3: ethane-1,2-diol / Heating
View Scheme
参考文献
El-Hamamy, Ahmad A.; Hill, John; Townend, John
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 573 - 580
反应条件
1: 52 percent / quinoline, sodium carbonate / 2-methoxy-ethanol / 0.75 h / Heating
2: ethane-1,2-diol / Heating
View Scheme
参考文献
El-Hamamy, Ahmad A.; Hill, John; Townend, John
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 573 - 580
反应条件
1.1: sodium / ethanol / 20 h / 100 °C / |Sealed tube; |Darkness
2.1: copper(l) iodide; potassium carbonate; N,N-dimethylethylenediamine / toluene / 24 h / 110 °C / |Schlenk technique; |Inert atmosphere
2.2: 1 h / 90 °C
View Scheme
参考文献
Zhan, Fuxu; Liang, Guangxin
Angewandte Chemie - International Edition, 2013 , vol. 52, # 4 p. 1266 - 1269
Angew. Chem., 2012 , vol. 125, # 4 p. 1304 - 1307,4
反应条件
1.1: triphenyl phosphite; bromine; triethylamine / dichloromethane / 20 h / -60 - 20 °C / |Inert atmosphere; |Reflux
2.1: copper(l) iodide; potassium carbonate; N,N-dimethylethylenediamine / toluene / 24 h / 110 °C / |Schlenk technique; |Inert atmosphere
2.2: 1 h / 90 °C
View Scheme
参考文献
Zhan, Fuxu; Liang, Guangxin
Angewandte Chemie - International Edition, 2013 , vol. 52, # 4 p. 1266 - 1269
Angew. Chem., 2012 , vol. 125, # 4 p. 1304 - 1307,4
反应条件
1: (E,Z)-crotononitrile; palladium 10 on activated carbon / toluene / 12 h / 150 °C / |Sealed tube
2: zinc(II) chloride / 1,1-dimethylpropan-1-ol / 3 h / 130 °C / |Sealed tube
View Scheme
参考文献
Taddei, Maurizio; Mura, Manuel G.; Rajamaeki, Suvi; De Luca, Lidia; Porcheddu, Andrea
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 14-15 p. 3002 - 3013
反应条件
in diethyl ether
20 h; Irradiation;
参考文献
El-Hamamy, Ahmad A.; Hill, John; Townend, John
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 573 - 580
反应条件
ammonia; sodium; iron nitrate (III)
anschl. mit Methyljodid;
参考文献
Nakazaki; Isoe
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1159,1167
Chem.Abstr., 1957 , p. 17877
