4-乙酰基-3,5-二甲基-2-吡咯羧酸叔丁酯合成路线 （共 5 条）
反应条件
1: 1.) NaBH4, 2.) BF3*Et2O / 1.) THF, 5 deg C, 2.) THF, 25 deg C, 30 min 2: 1.) Br2, AcOH, 2.) HCO2H / 1.) RT, 12 h, 2.) reflux, 3 h View Scheme
参考文献
Chauhan, S M S; Vijayarahavan, B
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1991 , vol. 30, # 12 p. 1104 - 1107
反应条件
toluene-4-sulfonic acid T=200 - 210°C;
参考文献
Treibs; Hintermeier
Chemische Berichte, 1954 , vol. 87, p. 1163,1166
反应条件
sodium acetate; zinc; sodium nitrite
1.) water, acetic acid, 5 deg C, 18 h, 2.) acetic acid, 75 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Rezzano, Irene; Buldain, Graciela; Frydman, Benjamin
Journal of Organic Chemistry, 1986 , vol. 51, # 21 p. 3968 - 3972
反应条件
acetic acid; zinc; sodium nitrite
Reaktion ueber zwei Stufen;
参考文献
Treibs; Hintermeier
Chemische Berichte, 1954 , vol. 87, p. 1163,1166
反应条件
toluene-4-sulfonic acid; ethylene glycol in benzene
Heating;
参考文献
Smith, Kevin M.; Miura, Michiko; Tabba, Hani D.
Journal of Organic Chemistry, 1983 , vol. 48, # 24 p. 4779 - 4781
