2-甲氧基-6-甲基吡啶合成路线 （共 26 条）
反应条件
silver carbonate in dichloromethane
参考文献
Brodney, Michael A.; Padwa, Albert
Tetrahedron Letters, 1997 , vol. 38, # 35 p. 6153 - 6156
反应条件
sodium hydroxide in dichloromethane
参考文献
Pfizer Inc.
Patent: US6251904 B1, 2001 ;
反应条件
sodium in methanol; water
参考文献
US2003/125330 A1, ;
US 20030125330 A1
反应条件
in methanol T=20°C; 48 h; Heating / reflux;
参考文献
EP1847535 A1, ;
Page/Page column 123-124 ;
EP 1847535 A1
反应条件
sodium hydride in N,N-dimethyl-formamide T=100°C;
参考文献
Caprio, Vittorio; Mann, John
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 19 p. 3151 - 3155
反应条件
1: 82 percent / HBr, Br2, NaNO2, H2O / H2O / 1.) -25 deg C to room temp., 1 h 2: 80 percent / NaH / dimethylformamide / 100 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 19 p. 3151 - 3155
参考文献
Journal of the Chemical Society, , p. 2693,2697
反应条件
1: methanol With sodium 0.5 h; 2: 2-fluoro-6-methyl-pyridine 48 h; Reflux;
参考文献
Journal of Medicinal Chemistry, , vol. 52, # 9 p. 3084 - 3092
反应条件
n-butyllithium; 2-(dimethylamino)-ethanol in tetrahydrofuran; hexane 1.) 0 deg C, 1 h, 2.) 0 deg C, 1 h;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 20 p. 3071 - 3080
反应条件
n-butyllithium; 2-(dimethylamino)-ethanol in tetrahydrofuran; hexane 1.) 0 deg C, 1 h, 2.) 0 deg C, 1 h;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 20 p. 3071 - 3080
