1-(2-萘基)丙-1-酮合成路线 （共 24 条）
反应条件
2: (i) NaBH4, BF3-Et2O, (ii) H2, Pd-C View Scheme
参考文献
Pettit,G.R. et al.
Canadian Journal of Chemistry, 1966 , vol. 44, p. 1283 - 1291
参考文献
Rousset
Bulletin de la Societe Chimique de France, 1896 , vol. <3> 15, p. 61
反应条件
morpholine; sodium hydroxide; sulfur 1.) a) 29 h, reflux, b) ice, c) 15 h, roomtemp., 2.) water / 95percent ethanol, reflux, 10 h; Yield given. Multistep reaction;
参考文献
Bandyopadhyay, T.K.; Bhattacharya, A. J.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 10 p. 1015 - 1019
反应条件
AlCl3, aluminium chloride in 1,2-dichloro-ethane
T=35°C; Friedel Crafts acylation;
参考文献
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; PURDUE RESEARCH FOUNDATION
Patent: US2011/269834 A1, 2011 ;
Location in patent: Page/Page column 26 ;
反应条件
[Cp*Ru(CNCH3)3]+PF6-; potassium carbonate in acetonitrile
1 h; Inert atmosphereReflux;
参考文献
Bouziane, Asmae; Carboni, Bertrand; Bruneau, Christian; Carreaux, Francois; Renaud, Jean-Luc
Tetrahedron, 2008 , vol. 64, # 51 p. 11745 - 11750
反应条件
1: in diethyl ether
T=20°C; 21 h; Heating / reflux;
2: With hydrogenchloride in diethyl ether; water
参考文献
PROSIDION LIMITED
Patent: WO2006/85118 A2, 2006 ;
Location in patent: Page/Page column 18 ;
WO 2006/085118 A2
反应条件
bis (triortho-tolylphosphine)palladium(II) chloride in dimethyl sulfoxide
T=100°C; 14 h;
参考文献
Jean, Mickael; Renaulty, Jacques; Uriac, Philippe; Capet, Marc; Van De Weghe, Pierre
Organic Letters, 2007 , vol. 9, # 18 p. 3623 - 3625
反应条件
(NH4)2S2O8; [{(η5-C5Me5)RhCl}2(μ-Cl)2] in water
T=110°C; 3 h; Inert atmosphereSealed tube;
参考文献
Li, Yang; Xue, Dong; Lu, Wei; Wang, Chao; Liu, Zhao-Tie; Xiao, Jianliang
Organic Letters, 2014 , vol. 16, # 1 p. 66 - 69
反应条件
1: in diethyl ether
T=20 - 25°C; Grignard reaction; Inert atmosphere;
2: With hydrogenchloride; water in diethyl ether
T=0 - 20°C;
参考文献
Lukas, Ronald J.; Muresan, Ana Z.; Damaj, M. Imad; Blough, Bruce E.; Huang, Xiaodong; Navarro, Hernan A.; Mascarella, S. Wayne; Eaton, J. Brek; Marxer-Miller, Syndia K.; Carroll, F. Ivy
Journal of Medicinal Chemistry, 2010 , vol. 53, # 12 p. 4731 - 4748
反应条件
bis (triortho-tolylphosphine)palladium(II) chloride in dimethyl sulfoxide
T=100°C; 14 h;
参考文献
Jean, Mickael; Renaulty, Jacques; Uriac, Philippe; Capet, Marc; Van De Weghe, Pierre
Organic Letters, 2007 , vol. 9, # 18 p. 3623 - 3625
