1-(2-萘基)丙-1-酮合成路线 （共 24 条）
反应条件
in tetrahydrofuran; diethyl ether; ethyl acetate; Petroleum ether
参考文献
Hoffmann-La Roche Inc.
Patent: US6187905 B1, 2001 ;
US 6187905 B1
反应条件
sodium dichromate; sulfuric acid in dimethyl sulfoxide
参考文献
Chang, Lu; Kuang, Yulong; Qin, Bo; Zhou, Xin; Liu, Xiaohua; Lin, Lili; Feng, Xiaoming
Organic Letters, 2010 , vol. 12, # 10 p. 2214 - 2217
反应条件
aluminium trichloride; nitrobenzene
T=-5 - 0°C;
参考文献
Campbell; Chattaway
Proceedings of the Royal Society of London, Series B: Biological Sciences, 1942 , vol. 130, p. 435,443
反应条件
morpholine; [Ni0(1,5-cyclooctadiene)2]; potassium phosphate; trimethylphosphane in tetrahydrofuran; 1,4-dioxane
T=100°C; 2 h; Inert atmosphere;
参考文献
Ueno, Satoshi; Usui, Kazumi; Kuwano, Ryoichi
Synlett, 2011 , # 9 p. 1303 - 1307
反应条件
1: n-butyllithium
2: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / Reflux
View Scheme
参考文献
Hu, Bin; Meng, Meng; Jiang, Shanshan; Deng, Weiping
Chinese Journal of Chemistry, 2012 , vol. 30, # 6 p. 1289 - 1294
反应条件
aluminium trichloride in chloroform
T=35 - 40°C; Product distribution;
参考文献
Dumpis, M. A.; Kudryashova, N. I.; Khromov-Borisov, N. V.
Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 10 p. 1799 - 1803
Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 10 p. 2113 - 2117
反应条件
sodium amide; benzene
folgend Erhitzen des Reaktionsgemisches mit Methyljodid;
参考文献
Volmar
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1910 , vol. 150, p. 1176
参考文献
Arrowsmith,G.B. et al.
Journal of the Chemical Society, 1965 , p. 2072 - 2078
反应条件
(i) LiNH2, liq. NH3, THF, (ii) /BRN= 969135/; Multistep reaction;
参考文献
Mejer,S.; Marcinow,Z.
Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, 1976 , vol. 24, p. 175 - 180
反应条件
nachfolgend Behandlung der entstandenen Natriumverbindung mit Methyljodid;
参考文献
Volmar
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1910 , vol. 150, p. 1176
