4-(苯乙炔基)苯甲酸乙酯合成路线 （共 17 条）
反应条件
1: 3-phenyl-2-propynoic acid With silver(l) oxide in dimethyl sulfoxide Inert atmosphere; 2: 4-iodobenzoic acid ethyl ester With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; triphenylphosphine in dimethyl sulfoxide T=140°C; Sonogashira coupling; 3 h; Inert atmosphere;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 17 p. 2827 - 2832
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; triphenylphosphine; lithium iodide in N,N-dimethyl-formamide Sonogashira coupling; Inert atmosphere;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 17 p. 2827 - 2832
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; triphenylphosphine; lithium iodide in tetrahydrofuran Sonogashira coupling; Inert atmosphere;
参考文献
Advanced Synthesis and Catalysis, , vol. 351, # 17 p. 2827 - 2832
反应条件
1,3-dimethyl-imidazolidin-2-one; potassium carbonate; triphenylphosphine; copper(l) chloride T=120°C; 12 h;
参考文献
Tetrahedron Letters, , vol. 54, # 6 p. 518 - 521
反应条件
hydrogenchloride Combinatorial reaction / High throughput screening (HTS);
参考文献
US2007/43234 A1, ;
Page/Page column 56-57 ;
反应条件
C41H38BFeN3P2; hydrogen in tetrahydrofuran T=20 - 90°C; P=3000.3 Torr; 22 h; Inert atmosphere;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 52 p. 14131 - 14134
Angew. Chem., , vol. 125, # 52 p. 14381 - 14383
反应条件
triethylsilane; 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; water; copper(II) sulfate in toluene 24 h; Reflux; stereoselective reaction;
参考文献
Luo, Fang; Pan, Changduo; Wang, Wenhui; Ye, Zhishi; Cheng, Jiang
Tetrahedron, 2010 , vol. 66, # 6 p. 1399 - 1403
