1,2-二吡啶-3-基乙酮合成路线 (共 2 条)
反应条件
1: With XPhos precatalyst; potassium tert-butylate in toluene
T=60°C; 4 h; Inert atmosphere;
2: With ammonium chloride in water; toluene
T=20°C; Inert atmosphere;
参考文献
Biscoe, Mark R.; Buchwald, Stephen L.
Organic Letters, 2009 , vol. 11, # 8 p. 1773 - 1775
反应条件
ammonia; KNH2
anschliessend mit Nicotinsaeure-methylester in Aether behandeln;
参考文献
Miller et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 674