1,2,3-三甲氧基苯合成路线 （共 210 条）
参考文献
Kohn; Gruen
Monatshefte fuer Chemie, 1925 , vol. 46, p. 89
反应条件
1: acidic sulfate quinoline; glacial acetic acid; bromine
2: carbon tetrachloride; bromine
3: glacial acetic acid; fuming nitric acid
4: glacial acetic acid; hydrobromic acid
View Scheme
参考文献
Kohn; Gruen
Monatshefte fuer Chemie, 1925 , vol. 46, p. 89
反应条件
1) K
1) THF, RT, 24h, 2) THF, -20 deg C, 5h; Yield given. Multistep reaction;
参考文献
Azzena, Ugo; Denurra, Teresa; Melloni, Giovanni; Piroddi, Anna Maria
Journal of Organic Chemistry, 1990 , vol. 55, # 19 p. 5386 - 5390
反应条件
[Ir2(OMe)2(1,5-cyclooctadiene)2]; 3,4,7,8-tetra-methyl-1,10-phenanthroline in tetrahydrofuran
T=80°C; 2.5 h; GloveboxInert atmosphere; Reagent/catalyst;
参考文献
Preshlock, Sean M.; Ghaffari, Behnaz; Maligres, Peter E.; Krska, Shane W.; Maleczka, Robert E.; Smith, Milton R.
Journal of the American Chemical Society, 2013 , vol. 135, # 20 p. 7572 - 7582
反应条件
[Ir2(OMe)2(1,5-cyclooctadiene)2]; 3,4,7,8-tetra-methyl-1,10-phenanthroline in tetrahydrofuran
T=80°C; 2.5 h; GloveboxInert atmosphere;
参考文献
Preshlock, Sean M.; Ghaffari, Behnaz; Maligres, Peter E.; Krska, Shane W.; Maleczka, Robert E.; Smith, Milton R.
Journal of the American Chemical Society, 2013 , vol. 135, # 20 p. 7572 - 7582
反应条件
sodium acetate; copper dichloride
参考文献
Sarbhai,K.P.; Mathur,K.B.L.
Indian Journal of Chemistry, 1966 , vol. 4, p. 81 - 85
参考文献
Iinuma, Munekazu; Matsuura, Shin; Tanaka, Toshiyuki
Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 4 p. 1472 - 1476
反应条件
aluminium trichloride in 1,2-dichloro-ethane
T=0°C; 2 h; 2.) Room temp., 3 h;
参考文献
Nore; Honkanen
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 5 p. 985 - 987
反应条件
aluminium trichloride in 1,2-dichloro-ethane
1.) from 0 deg C to RT, 3 h, 2.) reflux, 1 h;
参考文献
Sato; Dan; Onuma; Tanaka; Aoki; Koga
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 1 p. 109 - 116
反应条件
aluminium trichloride in 1,2-dichloro-ethane
1.) from 0 deg C to RT, 3 h, 2.) reflux, 1 h;
参考文献
Sato; Dan; Onuma; Tanaka; Aoki; Koga
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 1 p. 109 - 116
