1,2,3-三甲氧基苯合成路线 （共 210 条）
反应条件
potassium in tetrahydrofuran 24 h; Ambient temperature;
参考文献
Azzena, Ugo; Denurra, Teresa; Melloni, Giovanni; Rassu, Gloria
Journal of the Chemical Society, Chemical Communications, 1987 , p. 1549 - 1550
反应条件
sodium in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=100°C; 2 h;
参考文献
Morey, Jeroni; Costa, Antoni; Deya, Pere M.; Suner, Guillem; Saa, Jose M.
Journal of Organic Chemistry, 1990 , vol. 55, p. 3902 - 3909
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; sodium hydride; N-methylaniline in diethyl ether; xylene
参考文献
Loubinoux, B.; Coudert, G.; Guillaumet, G.
Synthesis, 1980 , # 8 p. 638 - 640
反应条件
lithium chloride in N,N-dimethyl-formamide 48 h; Heating; Yield given. Yields of byproduct given;
参考文献
Bernard, Angela M.; Ghiani, M. Rossella; Piras, Pier Paolo; Rivoldini, Antonio
Synthesis, 1989 , # 4 p. 287 - 289
反应条件
1: 87 percent / TMSOTf / CH2Cl2 / 0.75 h / 20 °C 2: 84 percent / hydrazine hydrate / methanol / 1 h / Heating View Scheme
参考文献
Monti
Gazzetta Chimica Italiana, 1930 , vol. 60, p. 777,778
反应条件
1.1: titanium tetrachloride / dichloromethane / 0 - 20 °C / Inert atmosphere 2.1: selenium(IV) oxide; dihydrogen peroxide / tert-butyl alcohol / 1.5 h / 50 °C 3.1: triethylamine / methanol / 0 - 20 °C 4.1: potassium carbonate / acetone / 0 - 20 °C / Inert atmosphere 5.1: trichlorophosphate / 0.33 h / 20 °C 5.2: 6 h / 60 °C 6.1: selenium(IV) oxide; dihydrogen peroxide / tert-butyl alcohol / 2.5 h / 50 °C 7.1: triethylamine / methanol / 0 - 20 °C 8.1: potassium carbonate / acetone / 36 h / 20 °C / Inert atmosphere 9.1: AlCl3, aluminium chloride / dichloromethane / 0 - 20 °C 10.1: lithium hexamethyldisilazane / tetrahydrofuran / -30 - 0 °C / Inert atmosphere 11.1: trifluoroacetic acid / methanol / 24 h / 50 °C View Scheme
参考文献
Chemical Communications, , vol. 47, # 10 p. 2868 - 2870
反应条件
Erwaermen des Reaktionsprodukts mit wss. HCl;
参考文献
Birch
Journal of the Chemical Society, 1947 , p. 102,104
反应条件
1: 70 percent / PPA 2: 95 percent / H2O, OH- / methanol 3: 90 percent / H2 / 10 percent Pd/C / 760 Torr 4: 65 percent / PPA / 80 - 90 °C View Scheme
参考文献
Pelter, Andrew; Ward, Robert S.; Rao, Ramohan R.
Tetrahedron, 1985 , vol. 41, # 14 p. 2933 - 2938
反应条件
in acetonitrile Ambient temperature; Rate constant;
参考文献
Yagci, Y.; Schnabel, W.; Wilpert, A.; Bending, J.
Journal of the Chemical Society, Faraday Transactions, 1994 , vol. 90, # 2 p. 287 - 292
反应条件
1.1: titanium tetrachloride / dichloromethane / 0 - 20 °C / Inert atmosphere 2.1: selenium(IV) oxide; dihydrogen peroxide / tert-butyl alcohol / 1.5 h / 50 °C 3.1: triethylamine / methanol / 0 - 20 °C 4.1: potassium carbonate / acetone / 0 - 20 °C / Inert atmosphere 5.1: trichlorophosphate / 0.33 h / 20 °C 5.2: 6 h / 60 °C 6.1: selenium(IV) oxide; dihydrogen peroxide / tert-butyl alcohol / 2.5 h / 50 °C 7.1: triethylamine / methanol / 0 - 20 °C View Scheme
参考文献
Asakawa, Tomohiro; Hiza, Aiki; Nakayama, Miho; Inai, Makoto; Oyama, Dai; Koide, Hiroyuki; Shimizu, Kosuke; Wakimoto, Toshiyuki; Harada, Norihiro; Tsukada, Hideo; Oku, Naoto; Kan, Toshiyuki
Chemical Communications, 2011 , vol. 47, # 10 p. 2868 - 2870
