1,2,3,4-四氢喹啉合成路线 （共 372 条）
反应条件
in diethyl ether
88 h; Ambient temperature;
参考文献
Brown, Eric; Leze, Antoine; Touet, Joel
Tetrahedron Asymmetry, 1996 , vol. 7, # 7 p. 2029 - 2040
反应条件
1) 220 deg C - 250 deg C, 1 h, 2) 300 deg C;
参考文献
Stadlbauer, Wolfgang; Schmut, Otto; Kappe, Thomas
Monatshefte fuer Chemie, 1980 , vol. 111, p. 1005 - 1014
反应条件
sulfuric acid; sodium chloride; sodium nitrite in dichloromethane
参考文献
PROMEGA CORPORATION; CORONA, Cesear; KLAUBERT, Dieter; MCDOUGALL, Mark
Patent: WO2011/26085 A2, 2011 ;
Location in patent: Page/Page column 48 ;
反应条件
1.1: 74 percent / potassium carbonate; potassium iodide / dimethylformamide / 90 °C
2.1: POCl3 / 0.5 h / 2 °C
2.2: 80 percent / 4 h / 90 °C
View Scheme
参考文献
Jung, Byung-Jun; Lee, Jeong-Ik; Chu, Hye Yong; Do, Lee-Mi; Lee, Jaemin; Shim, Hong-Ku
Journal of Materials Chemistry, 2005 , vol. 15, # 25 p. 2470 - 2475
反应条件
potassium carbonate; potassium iodide in N,N-dimethyl-formamide
T=90°C;
参考文献
Wang, Hui; Lu, Zhikuan; Lord, Samuel J.; Willets, Katherine A.; Bertke, Jeffrey A.; Bunge, Scott D.; Moerner; Twieg, Robert J.
Tetrahedron, 2007 , vol. 63, # 1 p. 103 - 114
参考文献
I.G. Farbenind.
Patent: DE473871 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 1273
反应条件
1: FeCl3·6H2O / toluene / 8 h / 85 °C
2: di-isopropyl azodicarboxylate / acetonitrile / 1 h / 20 °C
View Scheme
参考文献
Ling, Xuege; Xiong, Yan; Huang, Ruofeng; Zhang, Xiaohui; Zhang, Shuting; Chen, Changguo
Journal of Organic Chemistry, 2013 , vol. 78, # 11 p. 5218 - 5226
反应条件
hydrogen fluoride; dihydrogen peroxide; SbF5
T=-20°C; 0.166667 h;
参考文献
Berrier, Christian; Jacquesy, Jean-Claude; Jouannetaud, Marie-Paule; Renoux, Alain
Tetrahedron Letters, 1986 , vol. 27, # 38 p. 4565 - 4568
反应条件
1: 88 percent / tetrahydrofuran / 16 h / Heating
2: 100 percent / acetonitrile / 24 h / 20 °C
3: 84 percent / triethylamine / CH2Cl2 / 24 h / 20 °C
View Scheme
参考文献
Batey, Robert A.; Santhakumar; Yoshina-Ishii, Chiaki; Taylor, Scott D.
Tetrahedron Letters, 1998 , vol. 39, # 35 p. 6267 - 6270
反应条件
1: 79.8 percent / acetic acid / Heating
2: potassium hydroxide / H2O / Heating
3: phosphorus pentoxide, kieselguhr / xylene / 1 h / Heating
View Scheme
参考文献
Crabb, Trevor A.; Soilleux, Stephanie L.
Tetrahedron, 1986 , vol. 42, # 19 p. 5407 - 5414
